Yasgar A - Search Results

1

Compound Management for Quantitative High-Throughput Screening.

Yasgar A, Shinn P, Jadhav A, Auld D, Michael S, Zheng W, Austin CP, Inglese J, Simeonov A. Yasgar A, et al. JALA Charlottesv Va. 2008 Apr;13(2):79-89. doi: 10.1016/j.jala.2007.12.004. JALA Charlottesv Va. 2008. PMID: 18496600 Free PMC article.

2

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP. Inglese J, et al. Among authors: yasgar a. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. doi: 10.1073/pnas.0604348103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864780 Free PMC article.

3

Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format.

Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J. Auld DS, et al. Among authors: yasgar a. Methods Enzymol. 2006;414:566-89. doi: 10.1016/S0076-6879(06)14029-X. Methods Enzymol. 2006. PMID: 17110211

4

Evaluation of micro-parallel liquid chromatography as a method for HTS-coupled actives verification.

Simeonov A, Yasgar A, Klumpp C, Zheng W, Shafqat N, Oppermann U, Austin CP, Inglese J. Simeonov A, et al. Among authors: yasgar a. Assay Drug Dev Technol. 2007 Dec;5(6):815-24. doi: 10.1089/adt.2007.097. Assay Drug Dev Technol. 2007. PMID: 18078381

5

Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction.

Simeonov A, Yasgar A, Jadhav A, Lokesh GL, Klumpp C, Michael S, Austin CP, Natarajan A, Inglese J. Simeonov A, et al. Among authors: yasgar a. Anal Biochem. 2008 Apr 1;375(1):60-70. doi: 10.1016/j.ab.2007.11.039. Epub 2007 Dec 5. Anal Biochem. 2008. PMID: 18158907 Free PMC article.

6

Quantitative high-throughput screening using a live-cell cAMP assay identifies small-molecule agonists of the TSH receptor.

Titus S, Neumann S, Zheng W, Southall N, Michael S, Klumpp C, Yasgar A, Shinn P, Thomas CJ, Inglese J, Gershengorn MC, Austin CP. Titus S, et al. Among authors: yasgar a. J Biomol Screen. 2008 Feb;13(2):120-7. doi: 10.1177/1087057107313786. Epub 2008 Jan 23. J Biomol Screen. 2008. PMID: 18216391 Free PMC article.

7

A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction.

Kimple AJ, Yasgar A, Hughes M, Jadhav A, Willard FS, Muller RE, Austin CP, Inglese J, Ibeanu GC, Siderovski DP, Simeonov A. Kimple AJ, et al. Among authors: yasgar a. Comb Chem High Throughput Screen. 2008 Jun;11(5):396-409. doi: 10.2174/138620708784534770. Comb Chem High Throughput Screen. 2008. PMID: 18537560 Free PMC article.

8

A high-throughput 1,536-well luminescence assay for glutathione S-transferase activity.

Yasgar A, Shultz J, Zhou W, Wang H, Huang F, Murphy N, Abel EL, DiGiovanni J, Inglese J, Simeonov A. Yasgar A, et al. Assay Drug Dev Technol. 2010 Apr;8(2):200-11. doi: 10.1089/adt.2009.0248. Assay Drug Dev Technol. 2010. PMID: 20085484 Free PMC article.

9

A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase.

Yasgar A, Foley TL, Jadhav A, Inglese J, Burkart MD, Simeonov A. Yasgar A, et al. Mol Biosyst. 2010 Feb;6(2):365-75. doi: 10.1039/b913291k. Epub 2009 Oct 13. Mol Biosyst. 2010. PMID: 20094656 Free PMC article.

10

Preparation of FRET reporters to support chemical probe development.

Foley TL, Yasgar A, Garcia CJ, Jadhav A, Simeonov A, Burkart MD. Foley TL, et al. Among authors: yasgar a. Org Biomol Chem. 2010 Oct 21;8(20):4601-6. doi: 10.1039/c0ob00322k. Epub 2010 Aug 20. Org Biomol Chem. 2010. PMID: 20725690 Free PMC article.

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