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Page 1
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, D'Angelica M, Kemeny N, Lyden D, Rafii S. Shmelkov SV, et al. J Clin Invest. 2008 Jun;118(6):2111-20. doi: 10.1172/JCI34401. J Clin Invest. 2008. PMID: 18497886 Free PMC article.
AC133/CD133/Prominin-1.
Shmelkov SV, St Clair R, Lyden D, Rafii S. Shmelkov SV, et al. Int J Biochem Cell Biol. 2005 Apr;37(4):715-9. doi: 10.1016/j.biocel.2004.08.010. Int J Biochem Cell Biol. 2005. PMID: 15694831 Review.
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.
Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, Rafii S. Seandel M, et al. Among authors: shmelkov sv. Nature. 2007 Sep 20;449(7160):346-50. doi: 10.1038/nature06129. Nature. 2007. PMID: 17882221 Free PMC article.
Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene.
Seandel M, Butler JM, Kobayashi H, Hooper AT, White IA, Zhang F, Vertes EL, Kobayashi M, Zhang Y, Shmelkov SV, Hackett NR, Rabbany S, Boyer JL, Rafii S. Seandel M, et al. Among authors: shmelkov sv. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19288-93. doi: 10.1073/pnas.0805980105. Epub 2008 Nov 26. Proc Natl Acad Sci U S A. 2008. PMID: 19036927 Free PMC article.
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.
Hooper AT, Shmelkov SV, Gupta S, Milde T, Bambino K, Gillen K, Goetz M, Chavala S, Baljevic M, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, Vahdat L, Evans T, Rafii S. Hooper AT, et al. Among authors: shmelkov sv. Circ Res. 2009 Jul 17;105(2):201-8. doi: 10.1161/CIRCRESAHA.109.196790. Epub 2009 Jun 18. Circ Res. 2009. PMID: 19542015 Free PMC article.
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche.
Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. Kaplan RN, et al. Among authors: shmelkov sv. Nature. 2005 Dec 8;438(7069):820-7. doi: 10.1038/nature04186. Nature. 2005. PMID: 16341007 Free PMC article.
Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice.
Shmelkov SV, Hormigo A, Jing D, Proenca CC, Bath KG, Milde T, Shmelkov E, Kushner JS, Baljevic M, Dincheva I, Murphy AJ, Valenzuela DM, Gale NW, Yancopoulos GD, Ninan I, Lee FS, Rafii S. Shmelkov SV, et al. Nat Med. 2010 May;16(5):598-602, 1p following 602. doi: 10.1038/nm.2125. Epub 2010 Apr 25. Nat Med. 2010. PMID: 20418887 Free PMC article.
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