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Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques.
Halwani R, Boyer JD, Yassine-Diab B, Haddad EK, Robinson TM, Kumar S, Parkinson R, Wu L, Sidhu MK, Phillipson-Weiner R, Pavlakis GN, Felber BK, Lewis MG, Shen A, Siliciano RF, Weiner DB, Sekaly RP. Halwani R, et al. Among authors: wu l. J Immunol. 2008 Jun 15;180(12):7969-79. doi: 10.4049/jimmunol.180.12.7969. J Immunol. 2008. PMID: 18523260 Clinical Trial.
Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid.
Boyer JD, Robinson TM, Kutzler MA, Vansant G, Hokey DA, Kumar S, Parkinson R, Wu L, Sidhu MK, Pavlakis GN, Felber BK, Brown C, Silvera P, Lewis MG, Monforte J, Waldmann TA, Eldridge J, Weiner DB. Boyer JD, et al. Among authors: wu l. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18648-53. doi: 10.1073/pnas.0709198104. Epub 2007 Nov 13. Proc Natl Acad Sci U S A. 2007. PMID: 18000037 Free PMC article.
Co-immunization with an optimized plasmid-encoded immune stimulatory interleukin, high-mobility group box 1 protein, results in enhanced interferon-gamma secretion by antigen-specific CD8 T cells.
Muthumani G, Laddy DJ, Sundaram SG, Fagone P, Shedlock DJ, Kannan S, Wu L, Chung CW, Lankaraman KM, Burns J, Muthumani K, Weiner DB. Muthumani G, et al. Among authors: wu l. Immunology. 2009 Sep;128(1 Suppl):e612-20. doi: 10.1111/j.1365-2567.2009.03044.x. Epub 2009 Jan 12. Immunology. 2009. PMID: 19740322 Free PMC article.
Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus.
Muthumani K, Lankaraman KM, Laddy DJ, Sundaram SG, Chung CW, Sako E, Wu L, Khan A, Sardesai N, Kim JJ, Vijayachari P, Weiner DB. Muthumani K, et al. Among authors: wu l. Vaccine. 2008 Sep 19;26(40):5128-34. doi: 10.1016/j.vaccine.2008.03.060. Epub 2008 Apr 14. Vaccine. 2008. PMID: 18471943 Free PMC article.
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