Melnick A - Search Results

1

BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner.

Ranuncolo SM, Wang L, Polo JM, Dell'Oso T, Dierov J, Gaymes TJ, Rassool F, Carroll M, Melnick A. Ranuncolo SM, et al. Among authors: melnick a. J Biol Chem. 2008 Aug 15;283(33):22565-72. doi: 10.1074/jbc.M803490200. Epub 2008 Jun 4. J Biol Chem. 2008. PMID: 18524763 Free PMC article.

2

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

Polo JM, Dell'Oso T, Ranuncolo SM, Cerchietti L, Beck D, Da Silva GF, Prive GG, Licht JD, Melnick A. Polo JM, et al. Among authors: melnick a. Nat Med. 2004 Dec;10(12):1329-35. doi: 10.1038/nm1134. Epub 2004 Nov 7. Nat Med. 2004. PMID: 15531890

3

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

Polo JM, Juszczynski P, Monti S, Cerchietti L, Ye K, Greally JM, Shipp M, Melnick A. Polo JM, et al. Among authors: melnick a. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3207-12. doi: 10.1073/pnas.0611399104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360630 Free PMC article.

4

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms.

Parekh S, Polo JM, Shaknovich R, Juszczynski P, Lev P, Ranuncolo SM, Yin Y, Klein U, Cattoretti G, Dalla Favera R, Shipp MA, Melnick A. Parekh S, et al. Among authors: melnick a. Blood. 2007 Sep 15;110(6):2067-74. doi: 10.1182/blood-2007-01-069575. Epub 2007 Jun 1. Blood. 2007. PMID: 17545502 Free PMC article.

5

Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR.

Ranuncolo SM, Polo JM, Dierov J, Singer M, Kuo T, Greally J, Green R, Carroll M, Melnick A. Ranuncolo SM, et al. Among authors: melnick a. Nat Immunol. 2007 Jul;8(7):705-14. doi: 10.1038/ni1478. Epub 2007 Jun 10. Nat Immunol. 2007. PMID: 17558410

6

CtBP is an essential corepressor for BCL6 autoregulation.

Mendez LM, Polo JM, Yu JJ, Krupski M, Ding BB, Melnick A, Ye BH. Mendez LM, et al. Among authors: melnick a. Mol Cell Biol. 2008 Apr;28(7):2175-86. doi: 10.1128/MCB.01400-07. Epub 2008 Jan 22. Mol Cell Biol. 2008. PMID: 18212045 Free PMC article.

7

BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells.

Ranuncolo SM, Polo JM, Melnick A. Ranuncolo SM, et al. Among authors: melnick a. Blood Cells Mol Dis. 2008 Jul-Aug;41(1):95-9. doi: 10.1016/j.bcmd.2008.02.003. Epub 2008 Mar 17. Blood Cells Mol Dis. 2008. PMID: 18346918 Free PMC article.

8

Sequential transcription factor targeting for diffuse large B-cell lymphomas.

Cerchietti LC, Polo JM, Da Silva GF, Farinha P, Shaknovich R, Gascoyne RD, Dowdy SF, Melnick A. Cerchietti LC, et al. Among authors: melnick a. Cancer Res. 2008 May 1;68(9):3361-9. doi: 10.1158/0008-5472.CAN-07-5817. Cancer Res. 2008. PMID: 18451163 Free PMC article.

9

Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas.

Parekh S, Privé G, Melnick A. Parekh S, et al. Among authors: melnick a. Leuk Lymphoma. 2008 May;49(5):874-82. doi: 10.1080/10428190801895345. Leuk Lymphoma. 2008. PMID: 18452090 Free PMC article. Review.

10

Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells.

Polo JM, Ci W, Licht JD, Melnick A. Polo JM, et al. Among authors: melnick a. Blood. 2008 Aug 1;112(3):644-51. doi: 10.1182/blood-2008-01-131813. Epub 2008 May 16. Blood. 2008. PMID: 18487509 Free PMC article.

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