Krokan HE - Search Results

1

Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.

Westbye MP, Feyzi E, Aas PA, Vågbø CB, Talstad VA, Kavli B, Hagen L, Sundheim O, Akbari M, Liabakk NB, Slupphaug G, Otterlei M, Krokan HE. Westbye MP, et al. Among authors: krokan he. J Biol Chem. 2008 Sep 5;283(36):25046-56. doi: 10.1074/jbc.M803776200. Epub 2008 Jul 3. J Biol Chem. 2008. PMID: 18603530 Free PMC article.

2

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup.

Kavli B, Sundheim O, Akbari M, Otterlei M, Nilsen H, Skorpen F, Aas PA, Hagen L, Krokan HE, Slupphaug G. Kavli B, et al. Among authors: krokan he. J Biol Chem. 2002 Oct 18;277(42):39926-36. doi: 10.1074/jbc.M207107200. Epub 2002 Aug 2. J Biol Chem. 2002. PMID: 12161446 Free article.

3

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.

Aas PA, Otterlei M, Falnes PO, Vågbø CB, Skorpen F, Akbari M, Sundheim O, Bjørås M, Slupphaug G, Seeberg E, Krokan HE. Aas PA, et al. Among authors: krokan he. Nature. 2003 Feb 20;421(6925):859-63. doi: 10.1038/nature01363. Nature. 2003. PMID: 12594517

4

Novel aspects of macromolecular repair and relationship to human disease.

Krokan HE, Kavli B, Slupphaug G. Krokan HE, et al. J Mol Med (Berl). 2004 May;82(5):280-97. doi: 10.1007/s00109-004-0528-1. Epub 2004 Feb 24. J Mol Med (Berl). 2004. PMID: 14985856 Review.

5

Alkylation damage in DNA and RNA--repair mechanisms and medical significance.

Drabløs F, Feyzi E, Aas PA, Vaagbø CB, Kavli B, Bratlie MS, Peña-Diaz J, Otterlei M, Slupphaug G, Krokan HE. Drabløs F, et al. Among authors: krokan he. DNA Repair (Amst). 2004 Nov 2;3(11):1389-407. doi: 10.1016/j.dnarep.2004.05.004. DNA Repair (Amst). 2004. PMID: 15380096 Review.

6

Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.

Sundheim O, Vågbø CB, Bjørås M, Sousa MM, Talstad V, Aas PA, Drabløs F, Krokan HE, Tainer JA, Slupphaug G. Sundheim O, et al. Among authors: krokan he. EMBO J. 2006 Jul 26;25(14):3389-97. doi: 10.1038/sj.emboj.7601219. Epub 2006 Jul 6. EMBO J. 2006. PMID: 16858410 Free PMC article.

7

RNA base damage and repair.

Feyzi E, Sundheim O, Westbye MP, Aas PA, Vågbø CB, Otterlei M, Slupphaug G, Krokan HE. Feyzi E, et al. Among authors: krokan he. Curr Pharm Biotechnol. 2007 Dec;8(6):326-31. doi: 10.2174/138920107783018363. Curr Pharm Biotechnol. 2007. PMID: 18289040 Review.

8

AlkB demethylases flip out in different ways.

Sundheim O, Talstad VA, Vågbø CB, Slupphaug G, Krokan HE. Sundheim O, et al. Among authors: krokan he. DNA Repair (Amst). 2008 Nov 1;7(11):1916-23. doi: 10.1016/j.dnarep.2008.07.015. Epub 2008 Sep 6. DNA Repair (Amst). 2008. PMID: 18723127 Review.

9

Identification of a novel, widespread, and functionally important PCNA-binding motif.

Gilljam KM, Feyzi E, Aas PA, Sousa MM, Müller R, Vågbø CB, Catterall TC, Liabakk NB, Slupphaug G, Drabløs F, Krokan HE, Otterlei M. Gilljam KM, et al. Among authors: krokan he. J Cell Biol. 2009 Sep 7;186(5):645-54. doi: 10.1083/jcb.200903138. J Cell Biol. 2009. PMID: 19736315 Free PMC article.

10

Divergent ß-hairpins determine double-strand versus single-strand substrate recognition of human AlkB-homologues 2 and 3.

Monsen VT, Sundheim O, Aas PA, Westbye MP, Sousa MM, Slupphaug G, Krokan HE. Monsen VT, et al. Among authors: krokan he. Nucleic Acids Res. 2010 Oct;38(19):6447-55. doi: 10.1093/nar/gkq518. Epub 2010 Jun 4. Nucleic Acids Res. 2010. PMID: 20525795 Free PMC article.

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