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Expression of the transcriptional repressor Gfi-1 is regulated by C/EBP{alpha} and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells.
Lidonnici MR, Audia A, Soliera AR, Prisco M, Ferrari-Amorotti G, Waldron T, Donato N, Zhang Y, Martinez RV, Holyoake TL, Calabretta B. Lidonnici MR, et al. Among authors: martinez rv. Cancer Res. 2010 Oct 15;70(20):7949-59. doi: 10.1158/0008-5472.CAN-10-1667. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924107 Free PMC article.
The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain.
Ferrari-Amorotti G, Mariani SA, Novi C, Cattelani S, Pecorari L, Corradini F, Soliera AR, Manzotti G, Fragliasso V, Zhang Y, Martinez RV, Lam EW, Guerzoni C, Calabretta B. Ferrari-Amorotti G, et al. Among authors: martinez rv. J Biol Chem. 2010 Oct 1;285(40):30837-50. doi: 10.1074/jbc.M110.128272. Epub 2010 Jul 20. J Biol Chem. 2010. PMID: 20659895 Free PMC article.
81 results