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Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors.
Xin Z, Zhao H, Serby MD, Liu B, Liu M, Szczepankiewicz BG, Nelson LT, Smith HT, Suhar TS, Janis RS, Cao N, Camp HS, Collins CA, Sham HL, Surowy TK, Liu G. Xin Z, et al. Among authors: liu m, liu b, liu g. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4298-302. doi: 10.1016/j.bmcl.2008.06.088. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18632269
Pharmacology of A-216546: a highly selective antagonist for endothelin ET(A) receptor.
Wu-Wong JR, Dixon DB, Chiou WJ, Dayton BD, Novosad EI, Adler AL, Wessale JL, Calzadilla SV, Hernandez L, Marsh KC, Liu G, Szczepankiewicz B, von Geldern TW, Opgenorth TJ. Wu-Wong JR, et al. Among authors: liu g. Eur J Pharmacol. 1999 Feb 5;366(2-3):189-201. doi: 10.1016/s0014-2999(98)00891-7. Eur J Pharmacol. 1999. PMID: 10082200
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead.
Liu G, Link JT, Pei Z, Reilly EB, Leitza S, Nguyen B, Marsh KC, Okasinski GF, von Geldern TW, Ormes M, Fowler K, Gallatin M. Liu G, et al. J Med Chem. 2000 Oct 19;43(21):4025-40. doi: 10.1021/jm0002782. J Med Chem. 2000. PMID: 11052808
Discovery of potent antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 3. Amide (C-ring) structure-activity relationship and improvement of overall properties of arylthio cinnamides.
Pei Z, Xin Z, Liu G, Li Y, Reilly EB, Lubbers NL, Huth JR, Link JT, von Geldern TW, Cox BF, Leitza S, Gao Y, Marsh KC, DeVries P, Okasinski GF. Pei Z, et al. Among authors: liu g. J Med Chem. 2001 Aug 30;44(18):2913-20. doi: 10.1021/jm010059w. J Med Chem. 2001. PMID: 11520199
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 4. Structure-activity relationship of substituents on the benzene ring of the cinnamide.
Winn M, Reilly EB, Liu G, Huth JR, Jae HS, Freeman J, Pei Z, Xin Z, Lynch J, Kester J, von Geldern TW, Leitza S, DeVries P, Dickinson R, Mussatto D, Okasinski GF. Winn M, et al. Among authors: liu g. J Med Chem. 2001 Dec 6;44(25):4393-403. doi: 10.1021/jm0103108. J Med Chem. 2001. PMID: 11728185
35,031 results
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