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121 results

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Page 1
Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors.
Xin Z, Zhao H, Serby MD, Liu B, Liu M, Szczepankiewicz BG, Nelson LT, Smith HT, Suhar TS, Janis RS, Cao N, Camp HS, Collins CA, Sham HL, Surowy TK, Liu G. Xin Z, et al. Among authors: smith ht. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4298-302. doi: 10.1016/j.bmcl.2008.06.088. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18632269
Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
Liu G, Lynch JK, Freeman J, Liu B, Xin Z, Zhao H, Serby MD, Kym PR, Suhar TS, Smith HT, Cao N, Yang R, Janis RS, Krauser JA, Cepa SP, Beno DW, Sham HL, Collins CA, Surowy TK, Camp HS. Liu G, et al. Among authors: smith ht. J Med Chem. 2007 Jun 28;50(13):3086-100. doi: 10.1021/jm070219p. Epub 2007 May 27. J Med Chem. 2007. PMID: 17530838
Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.
Comess KM, Sun C, Abad-Zapatero C, Goedken ER, Gum RJ, Borhani DW, Argiriadi M, Groebe DR, Jia Y, Clampit JE, Haasch DL, Smith HT, Wang S, Song D, Coen ML, Cloutier TE, Tang H, Cheng X, Quinn C, Liu B, Xin Z, Liu G, Fry EH, Stoll V, Ng TI, Banach D, Marcotte D, Burns DJ, Calderwood DJ, Hajduk PJ. Comess KM, et al. Among authors: smith ht. ACS Chem Biol. 2011 Mar 18;6(3):234-44. doi: 10.1021/cb1002619. Epub 2011 Jan 20. ACS Chem Biol. 2011. PMID: 21090814
Inhibition of p56(lck) tyrosine kinase by isothiazolones.
Trevillyan JM, Chiou XG, Ballaron SJ, Tang QM, Buko A, Sheets MP, Smith ML, Putman CB, Wiedeman P, Tu N, Madar D, Smith HT, Gubbins EJ, Warrior UP, Chen YW, Mollison KW, Faltynek CR, Djurić SW. Trevillyan JM, et al. Among authors: smith ml, smith ht. Arch Biochem Biophys. 1999 Apr 1;364(1):19-29. doi: 10.1006/abbi.1999.1099. Arch Biochem Biophys. 1999. PMID: 10087161
Oxygen production from dissociation of Europa's water-ice surface.
Szalay JR, Allegrini F, Ebert RW, Bagenal F, Bolton SJ, Fatemi S, McComas DJ, Pontoni A, Saur J, Smith HT, Strobel DF, Vance SD, Vorburger A, Wilson RJ. Szalay JR, et al. Among authors: smith ht. Nat Astron. 2024;8(5):567-576. doi: 10.1038/s41550-024-02206-x. Epub 2024 Mar 4. Nat Astron. 2024. PMID: 38798715 Free PMC article.
Pruritus in primary biliary cholangitis is under-recorded in patient medical records.
Gungabissoon U, Smith HT, von Maltzahn R, Logie J, Fairburn-Beech J, Ma L, P D, McGirr A, Hunnicutt JN, Rowe CL, Tierney M, Friedler HS. Gungabissoon U, et al. Among authors: smith ht. BMJ Open Gastroenterol. 2024 Mar 27;11(1):e001287. doi: 10.1136/bmjgast-2023-001287. BMJ Open Gastroenterol. 2024. PMID: 38538090 Free PMC article.
121 results