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Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations.
Ellrichmann M, Kapelle M, Ritter PR, Holst JJ, Herzig KH, Schmidt WE, Schmitz F, Meier JJ. Ellrichmann M, et al. Among authors: schmitz f. J Clin Endocrinol Metab. 2008 Oct;93(10):3995-8. doi: 10.1210/jc.2008-0924. Epub 2008 Jul 22. J Clin Endocrinol Metab. 2008. PMID: 18647814 Clinical Trial.
The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.
Meier JJ, Gethmann A, Nauck MA, Götze O, Schmitz F, Deacon CF, Gallwitz B, Schmidt WE, Holst JJ. Meier JJ, et al. Among authors: schmitz f. Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1118-23. doi: 10.1152/ajpendo.00576.2005. Epub 2006 Jan 10. Am J Physiol Endocrinol Metab. 2006. PMID: 16403774 Free article.
Valine-286 residue in the third intracellular loop of the cholecystokinin 2 receptor exerts a pivotal role in cholecystokinin 2 receptor mediated intracellular signal transduction in human colon cancer cells.
Yu HG, Schäfer H, Mergler S, Müerköster S, Cramer T, Höcker M, Herzig KH, Schmidt WE, Schmitz F. Yu HG, et al. Among authors: schmitz f. Cell Signal. 2005 Dec;17(12):1505-15. doi: 10.1016/j.cellsig.2005.03.009. Cell Signal. 2005. PMID: 15951156
625 results