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Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.
Yang Z, Chen Y, Lillo C, Chien J, Yu Z, Michaelides M, Klein M, Howes KA, Li Y, Kaminoh Y, Chen H, Zhao C, Chen Y, Al-Sheikh YT, Karan G, Corbeil D, Escher P, Kamaya S, Li C, Johnson S, Frederick JM, Zhao Y, Wang C, Cameron DJ, Huttner WB, Schorderet DF, Munier FL, Moore AT, Birch DG, Baehr W, Hunt DM, Williams DS, Zhang K. Yang Z, et al. Among authors: corbeil d. J Clin Invest. 2008 Aug;118(8):2908-16. doi: 10.1172/JCI35891. J Clin Invest. 2008. PMID: 18654668 Free PMC article.
Focus on molecules: prominin-1 (CD133).
Jászai J, Fargeas CA, Florek M, Huttner WB, Corbeil D. Jászai J, et al. Among authors: corbeil d. Exp Eye Res. 2007 Nov;85(5):585-6. doi: 10.1016/j.exer.2006.03.022. Epub 2006 Jun 2. Exp Eye Res. 2007. PMID: 16733052 Review. No abstract available.
Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration.
Zacchigna S, Oh H, Wilsch-Bräuninger M, Missol-Kolka E, Jászai J, Jansen S, Tanimoto N, Tonagel F, Seeliger M, Huttner WB, Corbeil D, Dewerchin M, Vinckier S, Moons L, Carmeliet P. Zacchigna S, et al. Among authors: corbeil d. J Neurosci. 2009 Feb 18;29(7):2297-308. doi: 10.1523/JNEUROSCI.2034-08.2009. J Neurosci. 2009. PMID: 19228982 Free PMC article.
134 results