Wolfenden R - Search Results

1

Free-flow electrophoresis for top-down proteomics by Fourier transform ion cyclotron resonance mass spectrometry.

Ouvry-Patat SA, Torres MP, Quek HH, Gelfand CA, O'Mullan P, Nissum M, Schroeder GK, Han J, Elliott M, Dryhurst D, Ausio J, Wolfenden R, Borchers CH. Ouvry-Patat SA, et al. Among authors: wolfenden r. Proteomics. 2008 Jul;8(14):2798-808. doi: 10.1002/pmic.200800079. Proteomics. 2008. PMID: 18655049

2

Fourier transform ion cyclotron resonance MS reveals the presence of a water molecule in an enzyme transition-state analogue complex.

Borchers CH, Marquez VE, Schroeder GK, Short SA, Snider MJ, Speir JP, Wolfenden R. Borchers CH, et al. Among authors: wolfenden r. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15341-5. doi: 10.1073/pnas.0406781101. Epub 2004 Oct 19. Proc Natl Acad Sci U S A. 2004. PMID: 15494437 Free PMC article.

3

The time required for water attack at the phosphorus atom of simple phosphodiesters and of DNA.

Schroeder GK, Lad C, Wyman P, Williams NH, Wolfenden R. Schroeder GK, et al. Among authors: wolfenden r. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4052-5. doi: 10.1073/pnas.0510879103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537483 Free PMC article.

4

The rate enhancement produced by the ribosome: an improved model.

Schroeder GK, Wolfenden R. Schroeder GK, et al. Among authors: wolfenden r. Biochemistry. 2007 Apr 3;46(13):4037-44. doi: 10.1021/bi602600p. Epub 2007 Mar 13. Biochemistry. 2007. PMID: 17352494

5

Rates of spontaneous disintegration of DNA and the rate enhancements produced by DNA glycosylases and deaminases.

Schroeder GK, Wolfenden R. Schroeder GK, et al. Among authors: wolfenden r. Biochemistry. 2007 Nov 27;46(47):13638-47. doi: 10.1021/bi701480f. Epub 2007 Nov 1. Biochemistry. 2007. PMID: 17973496

6

Synthesis of conformationally locked carbocyclic 1,3-diazepinone nucleosides as inhibitors of cytidine deaminase.

Ludek OR, Schroeder GK, Wolfenden R, Marquez VE. Ludek OR, et al. Among authors: wolfenden r. Nucleic Acids Symp Ser (Oxf). 2008;(52):659-60. doi: 10.1093/nass/nrn333. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776552 Free PMC article.

7

The rate of spontaneous cleavage of the glycosidic bond of adenosine.

Stockbridge RB, Schroeder GK, Wolfenden R. Stockbridge RB, et al. Among authors: wolfenden r. Bioorg Chem. 2010 Oct;38(5):224-8. doi: 10.1016/j.bioorg.2010.05.003. Epub 2010 Jun 4. Bioorg Chem. 2010. PMID: 20580404 Free PMC article.

8

Flight of a cytidine deaminase complex with an imperfect transition state analogue inhibitor: mass spectrometric evidence for the presence of a trapped water molecule.

Schroeder GK, Zhou L, Snider MJ, Chen X, Wolfenden R. Schroeder GK, et al. Among authors: wolfenden r. Biochemistry. 2012 Aug 14;51(32):6476-86. doi: 10.1021/bi300516u. Epub 2012 Aug 2. Biochemistry. 2012. PMID: 22775299

On the basis of its entropic origin, that shortfall was tentatively ascribed to the trapping of a water molecule in the enzyme-inhibitor complex, as had been observed earlier for product uridine [Snider, M. J., and Wolfenden, R. (2001) Biochemistry 40, 11364-11371]. …

On the basis of its entropic origin, that shortfall was tentatively ascribed to the trapping of a water molecule in the enzyme-inhibitor com …

9

Synthesis and conformational analysis of locked carbocyclic analogues of 1,3-diazepinone riboside, a high-affinity cytidine deaminase inhibitor.

Ludek OR, Schroeder GK, Liao C, Russ PL, Wolfenden R, Marquez VE. Ludek OR, et al. Among authors: wolfenden r. J Org Chem. 2009 Aug 21;74(16):6212-23. doi: 10.1021/jo901127a. J Org Chem. 2009. PMID: 19618900 Free PMC article.

10

Contrasting behavior of conformationally locked carbocyclic nucleosides of adenosine and cytidine as substrates for deaminases.

Marquez VE, Schroeder GK, Ludek OR, Siddiqui MA, Ezzitouni A, Wolfenden R. Marquez VE, et al. Among authors: wolfenden r. Nucleosides Nucleotides Nucleic Acids. 2009 May;28(5):614-32. doi: 10.1080/15257770903091904. Nucleosides Nucleotides Nucleic Acids. 2009. PMID: 20183605 Free PMC article.

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