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Characterizing short-lived protein folding intermediates by top-down hydrogen exchange mass spectrometry.
Pan J, Han J, Borchers CH, Konermann L. Pan J, et al. Anal Chem. 2010 Oct 15;82(20):8591-7. doi: 10.1021/ac101679j. Anal Chem. 2010. PMID: 20849085
The time-resolved experiments reported herein represent an extension of our previous work, where HDX/MS with top-down ECD was employed for monitoring "static" protein structures under equilibrium conditions (Pan et al. J. Am. Chem. Soc. 2009, 131, 12801)....
The time-resolved experiments reported herein represent an extension of our previous work, where HDX/MS with top-down ECD was employed for m …
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