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G3139, an anti-Bcl-2 antisense oligomer that binds heparin-binding growth factors and collagen I, alters in vitro endothelial cell growth and tubular morphogenesis.
Stein CA, Wu S, Voskresenskiy AM, Zhou JF, Shin J, Miller P, Souleimanian N, Benimetskaya L. Stein CA, et al. Among authors: benimetskaya l. Clin Cancer Res. 2009 Apr 15;15(8):2797-807. doi: 10.1158/1078-0432.CCR-08-2610. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351753 Free PMC article.
Antisense strategies for oncogene inactivation.
Stein CA, Benimetskaya L, Mani S. Stein CA, et al. Among authors: benimetskaya l. Semin Oncol. 2005 Dec;32(6):563-72. doi: 10.1053/j.seminoncol.2005.09.003. Semin Oncol. 2005. PMID: 16338422 Review.
Bcl-2 protein in 518A2 melanoma cells in vivo and in vitro.
Benimetskaya L, Ayyanar K, Kornblum N, Castanotto D, Rossi J, Wu S, Lai J, Brown BD, Popova N, Miller P, McMicken H, Chen Y, Stein CA. Benimetskaya L, et al. Clin Cancer Res. 2006 Aug 15;12(16):4940-8. doi: 10.1158/1078-0432.CCR-06-1002. Clin Cancer Res. 2006. PMID: 16914583
Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents.
Stein CA, Hansen JB, Lai J, Wu S, Voskresenskiy A, Høg A, Worm J, Hedtjärn M, Souleimanian N, Miller P, Soifer HS, Castanotto D, Benimetskaya L, Ørum H, Koch T. Stein CA, et al. Among authors: benimetskaya l. Nucleic Acids Res. 2010 Jan;38(1):e3. doi: 10.1093/nar/gkp841. Epub 2009 Oct 23. Nucleic Acids Res. 2010. PMID: 19854938 Free PMC article.
Induction of apoptosis by G3139 in melanoma cells.
Benimetskaya L, Lai JC, Khvorova A, Wu S, Miller P, Stein CA. Benimetskaya L, et al. Ann N Y Acad Sci. 2005 Nov;1058:235-45. doi: 10.1196/annals.1359.033. Ann N Y Acad Sci. 2005. PMID: 16394140 Review.
36 results