Tamboli IY - Search Results

1

Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid beta-protein in perivascular astrocytes.

Utter S, Tamboli IY, Walter J, Upadhaya AR, Birkenmeier G, Pietrzik CU, Ghebremedhin E, Thal DR. Utter S, et al. Among authors: tamboli iy. J Neuropathol Exp Neurol. 2008 Sep;67(9):842-56. doi: 10.1097/NEN.0b013e3181836a71. J Neuropathol Exp Neurol. 2008. PMID: 18716559

2

Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.

Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J. Tamboli IY, et al. J Biol Chem. 2005 Jul 29;280(30):28110-7. doi: 10.1074/jbc.M414525200. Epub 2005 May 27. J Biol Chem. 2005. PMID: 15923191 Free article.

3

Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.

Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Tamboli IY, et al. J Neurosci. 2008 Nov 12;28(46):12097-106. doi: 10.1523/JNEUROSCI.2635-08.2008. J Neurosci. 2008. PMID: 19005074 Free PMC article.

4

Sphingolipid storage impairs autophagic clearance of Alzheimer-associated proteins.

Tamboli IY, Tien NT, Walter J. Tamboli IY, et al. Autophagy. 2011 Jun;7(6):645-6. doi: 10.4161/auto.7.6.15122. Epub 2011 Jun 1. Autophagy. 2011. PMID: 21460623

5

Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein.

Tien NT, Karaca I, Tamboli IY, Walter J. Tien NT, et al. Among authors: tamboli iy. J Biol Chem. 2016 May 13;291(20):10528-40. doi: 10.1074/jbc.M116.719286. Epub 2016 Mar 8. J Biol Chem. 2016. PMID: 26957541 Free PMC article.

6

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.

Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, Lütjohann D, Wunderlich P, Walter J. Tamboli IY, et al. J Biol Chem. 2010 Nov 26;285(48):37405-14. doi: 10.1074/jbc.M110.149468. Epub 2010 Sep 28. J Biol Chem. 2010. PMID: 20876579 Free PMC article.

7

Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.

Tamboli IY, Hampel H, Tien NT, Tolksdorf K, Breiden B, Mathews PM, Saftig P, Sandhoff K, Walter J. Tamboli IY, et al. J Neurosci. 2011 Feb 2;31(5):1837-49. doi: 10.1523/JNEUROSCI.2954-10.2011. J Neurosci. 2011. PMID: 21289194 Free PMC article.

8

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

Koch P, Tamboli IY, Mertens J, Wunderlich P, Ladewig J, Stüber K, Esselmann H, Wiltfang J, Brüstle O, Walter J. Koch P, et al. Among authors: tamboli iy. Am J Pathol. 2012 Jun;180(6):2404-16. doi: 10.1016/j.ajpath.2012.02.012. Epub 2012 Apr 14. Am J Pathol. 2012. PMID: 22510327 Free article.

9

Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein.

Karaca I, Tamboli IY, Glebov K, Richter J, Fell LH, Grimm MO, Haupenthal VJ, Hartmann T, Gräler MH, van Echten-Deckert G, Walter J. Karaca I, et al. Among authors: tamboli iy. J Biol Chem. 2014 Jun 13;289(24):16761-72. doi: 10.1074/jbc.M113.535500. Epub 2014 May 7. J Biol Chem. 2014. PMID: 24808180 Free PMC article.

10

Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein.

Venkataramani V, Rossner C, Iffland L, Schweyer S, Tamboli IY, Walter J, Wirths O, Bayer TA. Venkataramani V, et al. Among authors: tamboli iy. J Biol Chem. 2010 Apr 2;285(14):10678-89. doi: 10.1074/jbc.M109.057836. Epub 2010 Feb 9. J Biol Chem. 2010. PMID: 20145244 Free PMC article.

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