Emanuel SL - Search Results

1

7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: design, synthesis, and biological activity.

Hughes TV, Emanuel SL, O'Grady HR, Connolly PJ, Rugg C, Fuentes-Pesquera AR, Karnachi P, Alexander R, Middleton SA. Hughes TV, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5130-3. doi: 10.1016/j.bmcl.2008.07.090. Epub 2008 Jul 26. Bioorg Med Chem Lett. 2008. PMID: 18718756

2

3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.

Lin R, Lu Y, Wetter SK, Connolly PJ, Turchi IJ, Murray WV, Emanuel SL, Gruninger RH, Fuentes-Pesquera AR, Adams M, Pandey N, Moreno-Mazza S, Middleton SA, Jolliffe LK. Lin R, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2005 May 2;15(9):2221-4. doi: 10.1016/j.bmcl.2005.03.024. Bioorg Med Chem Lett. 2005. PMID: 15837297

3

1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities.

Lin R, Connolly PJ, Huang S, Wetter SK, Lu Y, Murray WV, Emanuel SL, Gruninger RH, Fuentes-Pesquera AR, Rugg CA, Middleton SA, Jolliffe LK. Lin R, et al. Among authors: emanuel sl. J Med Chem. 2005 Jun 30;48(13):4208-11. doi: 10.1021/jm050267e. J Med Chem. 2005. PMID: 15974571

4

Synthesis and biological study of 4-aminopyrimidine-5-carboxaldehyde oximes as antiproliferative VEGFR-2 inhibitors.

Huang S, Li R, Connolly PJ, Xu G, Gaul MD, Emanuel SL, Lamontagne KR, Greenberger LM. Huang S, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6063-6. doi: 10.1016/j.bmcl.2006.08.107. Epub 2006 Sep 18. Bioorg Med Chem Lett. 2006. PMID: 16979339

5

Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor.

Huang S, Lin R, Yu Y, Lu Y, Connolly PJ, Chiu G, Li S, Emanuel SL, Middleton SA. Huang S, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1243-5. doi: 10.1016/j.bmcl.2006.12.031. Epub 2006 Dec 15. Bioorg Med Chem Lett. 2007. PMID: 17234412

6

4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: synthesis and biological evaluation.

Hughes TV, Emanuel SL, Beck AK, Wetter SK, Connolly PJ, Karnachi P, Reuman M, Seraj J, Fuentes-Pesquera AR, Gruninger RH, Middleton SA, Lin R, Davis JM, Moffat DF. Hughes TV, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3266-70. doi: 10.1016/j.bmcl.2007.04.021. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17481894

7

Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents.

Lin R, Connolly PJ, Lu Y, Chiu G, Li S, Yu Y, Huang S, Li X, Emanuel SL, Middleton SA, Gruninger RH, Adams M, Fuentes-Pesquera AR, Greenberger LM. Lin R, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4297-302. doi: 10.1016/j.bmcl.2007.05.029. Epub 2007 May 16. Bioorg Med Chem Lett. 2007. PMID: 17532631

8

Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors.

Lin R, Chiu G, Yu Y, Connolly PJ, Li S, Lu Y, Adams M, Fuentes-Pesquera AR, Emanuel SL, Greenberger LM. Lin R, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4557-61. doi: 10.1016/j.bmcl.2007.05.092. Epub 2007 Jun 6. Bioorg Med Chem Lett. 2007. PMID: 17574416

9

Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases.

Xu G, Searle LL, Hughes TV, Beck AK, Connolly PJ, Abad MC, Neeper MP, Struble GT, Springer BA, Emanuel SL, Gruninger RH, Pandey N, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Greenberger LM. Xu G, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3495-9. doi: 10.1016/j.bmcl.2008.05.024. Epub 2008 May 10. Bioorg Med Chem Lett. 2008. PMID: 18508264

10

4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors.

Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA. Xu G, et al. Among authors: emanuel sl. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. doi: 10.1016/j.bmcl.2008.07.020. Epub 2008 Jul 10. Bioorg Med Chem Lett. 2008. PMID: 18653333

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

43 results

Search Page

Filters