Rugg C - Search Results

1

7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: design, synthesis, and biological activity.

Hughes TV, Emanuel SL, O'Grady HR, Connolly PJ, Rugg C, Fuentes-Pesquera AR, Karnachi P, Alexander R, Middleton SA. Hughes TV, et al. Among authors: rugg c. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5130-3. doi: 10.1016/j.bmcl.2008.07.090. Epub 2008 Jul 26. Bioorg Med Chem Lett. 2008. PMID: 18718756

2

Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.

Kuo GH, Deangelis A, Emanuel S, Wang A, Zhang Y, Connolly PJ, Chen X, Gruninger RH, Rugg C, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV. Kuo GH, et al. Among authors: rugg c. J Med Chem. 2005 Jul 14;48(14):4535-46. doi: 10.1021/jm040214h. J Med Chem. 2005. PMID: 15999992

3

1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities.

Lin R, Connolly PJ, Huang S, Wetter SK, Lu Y, Murray WV, Emanuel SL, Gruninger RH, Fuentes-Pesquera AR, Rugg CA, Middleton SA, Jolliffe LK. Lin R, et al. J Med Chem. 2005 Jun 30;48(13):4208-11. doi: 10.1021/jm050267e. J Med Chem. 2005. PMID: 15974571

4

The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases.

Emanuel S, Rugg CA, Gruninger RH, Lin R, Fuentes-Pesquera A, Connolly PJ, Wetter SK, Hollister B, Kruger WW, Napier C, Jolliffe L, Middleton SA. Emanuel S, et al. Among authors: rugg ca. Cancer Res. 2005 Oct 1;65(19):9038-46. doi: 10.1158/0008-5472.CAN-05-0882. Cancer Res. 2005. PMID: 16204078

5

Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor.

Seamon JA, Rugg CA, Emanuel S, Calcagno AM, Ambudkar SV, Middleton SA, Butler J, Borowski V, Greenberger LM. Seamon JA, et al. Mol Cancer Ther. 2006 Oct;5(10):2459-67. doi: 10.1158/1535-7163.MCT-06-0339. Mol Cancer Ther. 2006. PMID: 17041089

6

Cellular and in vivo activity of JNJ-28871063, a nonquinazoline pan-ErbB kinase inhibitor that crosses the blood-brain barrier and displays efficacy against intracranial tumors.

Emanuel SL, Hughes TV, Adams M, Rugg CA, Fuentes-Pesquera A, Connolly PJ, Pandey N, Moreno-Mazza S, Butler J, Borowski V, Middleton SA, Gruninger RH, Story JR, Napier C, Hollister B, Greenberger LM. Emanuel SL, et al. Among authors: rugg ca. Mol Pharmacol. 2008 Feb;73(2):338-48. doi: 10.1124/mol.107.041236. Epub 2007 Nov 1. Mol Pharmacol. 2008. PMID: 17975007

7

Flow cytometric and morphological studies of ovarian carcinoma cell lines and xenografts.

van Haaften-Day C, Russell P, Rugg C, Wills EJ, Tattersall MH. van Haaften-Day C, et al. Among authors: rugg c. Cancer Res. 1983 Aug;43(8):3725-31. Cancer Res. 1983. PMID: 6861142

8

Association of DNA index and S-phase fraction with prognosis of nodes positive early breast cancer.

Hedley DW, Rugg CA, Gelber RD. Hedley DW, et al. Among authors: rugg ca. Cancer Res. 1987 Sep 1;47(17):4729-35. Cancer Res. 1987. PMID: 3621170

9

Influence of cellular DNA content on disease-free survival of Stage II breast cancer patients.

Hedley DW, Rugg CA, Ng AB, Taylor IW. Hedley DW, et al. Among authors: rugg ca. Cancer Res. 1984 Nov;44(11):5395-8. Cancer Res. 1984. PMID: 6488193

10

The prognostic significance of proliferative activity in poor histology non-Hodgkin's lymphoma: a flow cytometry study using archival material.

Young GA, Hedley DW, Rugg CA, Iland HJ. Young GA, et al. Among authors: rugg ca. Eur J Cancer Clin Oncol. 1987 Oct;23(10):1497-504. doi: 10.1016/0277-5379(87)90092-7. Eur J Cancer Clin Oncol. 1987. PMID: 3678313

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