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Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.
Ricarte-Filho JC, Ryder M, Chitale DA, Rivera M, Heguy A, Ladanyi M, Janakiraman M, Solit D, Knauf JA, Tuttle RM, Ghossein RA, Fagin JA. Ricarte-Filho JC, et al. Among authors: ryder m. Cancer Res. 2009 Jun 1;69(11):4885-93. doi: 10.1158/0008-5472.CAN-09-0727. Cancer Res. 2009. PMID: 19487299 Free PMC article.
Absence of common activating mutations of the epidermal growth factor receptor gene in thyroid cancers from American and Japanese patients.
Ricarte-Filho JC, Matsuse M, Lau C, Ryder M, Nishihara E, Ghossein RA, Ladanyi M, Yamashita S, Mitsutake N, Fagin JA. Ricarte-Filho JC, et al. Among authors: ryder m. Int J Cancer. 2012 May 1;130(9):2215-7; author reply 2217-8. doi: 10.1002/ijc.26267. Epub 2011 Aug 24. Int J Cancer. 2012. PMID: 21717456 Free PMC article. No abstract available.
Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation.
Chakravarty D, Santos E, Ryder M, Knauf JA, Liao XH, West BL, Bollag G, Kolesnick R, Thin TH, Rosen N, Zanzonico P, Larson SM, Refetoff S, Ghossein R, Fagin JA. Chakravarty D, et al. Among authors: ryder m. J Clin Invest. 2011 Dec;121(12):4700-11. doi: 10.1172/JCI46382. Epub 2011 Nov 21. J Clin Invest. 2011. PMID: 22105174 Free PMC article.
Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.
Montero-Conde C, Ruiz-Llorente S, Dominguez JM, Knauf JA, Viale A, Sherman EJ, Ryder M, Ghossein RA, Rosen N, Fagin JA. Montero-Conde C, et al. Among authors: ryder m. Cancer Discov. 2013 May;3(5):520-33. doi: 10.1158/2159-8290.CD-12-0531. Epub 2013 Jan 29. Cancer Discov. 2013. PMID: 23365119 Free PMC article.
367 results