Roberts JD - Search Results

1

Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.

Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, Dent P. Zhang G, et al. Among authors: roberts jd. Clin Cancer Res. 2008 Sep 1;14(17):5385-99. doi: 10.1158/1078-0432.CCR-08-0469. Clin Cancer Res. 2008. PMID: 18765530 Free PMC article.

2

Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.

Mitchell C, Park MA, Zhang G, Yacoub A, Curiel DT, Fisher PB, Roberts JD, Grant S, Dent P. Mitchell C, et al. Among authors: roberts jd. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3101-12. doi: 10.1158/1535-7163.MCT-07-0561. Epub 2007 Dec 7. Mol Cancer Ther. 2007. PMID: 18065490

3

Transient exposure of carcinoma cells to RAS/MEK inhibitors and UCN-01 causes cell death in vitro and in vivo.

Hamed H, Hawkins W, Mitchell C, Gilfor D, Zhang G, Pei XY, Dai Y, Hagan MP, Roberts JD, Yacoub A, Grant S, Dent P. Hamed H, et al. Among authors: roberts jd. Mol Cancer Ther. 2008 Mar;7(3):616-29. doi: 10.1158/1535-7163.MCT-07-2376. Mol Cancer Ther. 2008. PMID: 18347148

4

Transient exposure of mammary tumors to PD184352 and UCN-01 causes tumor cell death in vivo and prolonged suppression of tumor regrowth.

Hawkins W, Mitchell C, McKinstry R, Gilfor D, Starkey J, Dai Y, Dawson K, Ramakrishnan V, Roberts JD, Yacoub A, Grant S, Dent P. Hawkins W, et al. Among authors: roberts jd. Cancer Biol Ther. 2005 Nov;4(11):1275-84. doi: 10.4161/cbt.4.11.2286. Epub 2005 Dec 1. Cancer Biol Ther. 2005. PMID: 16319524 Free article.

5

Phase I trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-B-D-arabinofuranosylcytosine in patients with refractory acute leukemia.

Cragg LH, Andreeff M, Feldman E, Roberts J, Murgo A, Winning M, Tombes MB, Roboz G, Kramer L, Grant S. Cragg LH, et al. Clin Cancer Res. 2002 Jul;8(7):2123-33. Clin Cancer Res. 2002. PMID: 12114412 Clinical Trial.

6

Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.

Mitchell C, Kabolizadeh P, Ryan J, Roberts JD, Yacoub A, Curiel DT, Fisher PB, Hagan MP, Farrell NP, Grant S, Dent P. Mitchell C, et al. Among authors: roberts jd. Mol Pharmacol. 2007 Sep;72(3):704-14. doi: 10.1124/mol.107.038406. Epub 2007 Jun 19. Mol Pharmacol. 2007. PMID: 17578896

7

A phase I trial of vorinostat and alvocidib in patients with relapsed, refractory, or poor prognosis acute leukemia, or refractory anemia with excess blasts-2.

Holkova B, Supko JG, Ames MM, Reid JM, Shapiro GI, Perkins EB, Ramakrishnan V, Tombes MB, Honeycutt C, McGovern RM, Kmieciak M, Shrader E, Wellons MD, Sankala H, Doyle A, Wright J, Roberts JD, Grant S. Holkova B, et al. Among authors: roberts jd. Clin Cancer Res. 2013 Apr 1;19(7):1873-83. doi: 10.1158/1078-0432.CCR-12-2926. Epub 2013 Mar 20. Clin Cancer Res. 2013. PMID: 23515411 Free PMC article. Clinical Trial.

8

Phase I Study of Sorafenib and Vorinostat in Advanced Hepatocellular Carcinoma.

Gordon SW, McGuire WP 3rd, Shafer DA, Sterling RK, Lee HM, Matherly SC, Roberts JD, Bose P, Tombes MB, Shrader EE, Ryan AA, Kmieciak M, Nguyen T, Deng X, Bandyopadhyay D, Dent P, Poklepovic AS. Gordon SW, et al. Among authors: roberts jd. Am J Clin Oncol. 2019 Aug;42(8):649-654. doi: 10.1097/COC.0000000000000567. Am J Clin Oncol. 2019. PMID: 31305287 Clinical Trial.

9

The use of cyclin-dependent kinase inhibitors alone or in combination with established cytotoxic drugs in cancer chemotherapy.

Grant S, Roberts JD. Grant S, et al. Among authors: roberts jd. Drug Resist Updat. 2003 Feb;6(1):15-26. doi: 10.1016/s1368-7646(02)00141-3. Drug Resist Updat. 2003. PMID: 12654284 Review.

10

Phase I study of bryostatin 1 and fludarabine in patients with chronic lymphocytic leukemia and indolent (non-Hodgkin's) lymphoma.

Roberts JD, Smith MR, Feldman EJ, Cragg L, Millenson MM, Roboz GJ, Honeycutt C, Thune R, Padavic-Shaller K, Carter WH, Ramakrishnan V, Murgo AJ, Grant S. Roberts JD, et al. Clin Cancer Res. 2006 Oct 1;12(19):5809-16. doi: 10.1158/1078-0432.CCR-05-2730. Clin Cancer Res. 2006. PMID: 17020988 Clinical Trial.

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