Leppla SH - Search Results

1

Role of N-terminal amino acids in the potency of anthrax lethal factor.

Gupta PK, Moayeri M, Crown D, Fattah RJ, Leppla SH. Gupta PK, et al. Among authors: leppla sh. PLoS One. 2008 Sep 3;3(9):e3130. doi: 10.1371/journal.pone.0003130. PLoS One. 2008. PMID: 18769623 Free PMC article.

2

Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells.

Arora N, Klimpel KR, Singh Y, Leppla SH. Arora N, et al. Among authors: leppla sh. J Biol Chem. 1992 Aug 5;267(22):15542-8. J Biol Chem. 1992. PMID: 1639793 Free article.

3

The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity.

Singh Y, Klimpel KR, Quinn CP, Chaudhary VK, Leppla SH. Singh Y, et al. Among authors: leppla sh. J Biol Chem. 1991 Aug 15;266(23):15493-7. J Biol Chem. 1991. PMID: 1651334 Free article.

4

Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis.

Quinn CP, Singh Y, Klimpel KR, Leppla SH. Quinn CP, et al. Among authors: leppla sh. J Biol Chem. 1991 Oct 25;266(30):20124-30. J Biol Chem. 1991. PMID: 1939073 Free article.

5

Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity.

Klimpel KR, Arora N, Leppla SH. Klimpel KR, et al. Among authors: leppla sh. Mol Microbiol. 1994 Sep;13(6):1093-100. doi: 10.1111/j.1365-2958.1994.tb00500.x. Mol Microbiol. 1994. PMID: 7854123

6

Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells.

Arora N, Leppla SH. Arora N, et al. Among authors: leppla sh. Infect Immun. 1994 Nov;62(11):4955-61. doi: 10.1128/iai.62.11.4955-4961.1994. Infect Immun. 1994. PMID: 7927776 Free PMC article.

7

Cytotoxic effects of a chimeric protein consisting of tetanus toxin light chain and anthrax toxin lethal factor in non-neuronal cells.

Arora N, Williamson LC, Leppla SH, Halpern JL. Arora N, et al. Among authors: leppla sh. J Biol Chem. 1994 Oct 21;269(42):26165-71. J Biol Chem. 1994. PMID: 7929330 Free article.

8

Characterization of macrophage sensitivity and resistance to anthrax lethal toxin.

Friedlander AM, Bhatnagar R, Leppla SH, Johnson L, Singh Y. Friedlander AM, et al. Among authors: leppla sh. Infect Immun. 1993 Jan;61(1):245-52. doi: 10.1128/iai.61.1.245-252.1993. Infect Immun. 1993. PMID: 8380282 Free PMC article.

9

Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides.

Arora N, Leppla SH. Arora N, et al. Among authors: leppla sh. J Biol Chem. 1993 Feb 15;268(5):3334-41. J Biol Chem. 1993. PMID: 8429009 Free article.

10

A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen.

Gordon VM, Rehemtulla A, Leppla SH. Gordon VM, et al. Among authors: leppla sh. Infect Immun. 1997 Aug;65(8):3370-5. doi: 10.1128/iai.65.8.3370-3375.1997. Infect Immun. 1997. PMID: 9234799 Free PMC article.

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