Leroy F - Search Results

1

Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.

Leroy F, Chaves D, Dukhan D, Storer R, Sommadossi JP, Loi AG, Cadeddu A, Fanti M, Boscu N, Bassetti F, Liuzzi M, Gosselin G. Leroy F, et al. Nucleic Acids Symp Ser (Oxf). 2008;(52):595-6. doi: 10.1093/nass/nrn301. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776520

2

Synthesis and antiviral evaluation of 4-fluoropyrazole-3-carboxamide nucleoside derivatives.

Leroy F, Chaves D, Dukhan D, Storer R, Sommadossi JP, Loi AG, Cadeddu A, Fanti M, Boscu N, Bassetti F, Liuzzi M, Gosselin G. Leroy F, et al. Nucleic Acids Symp Ser (Oxf). 2008;(52):617-8. doi: 10.1093/nass/nrn312. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776531

3

Synthesis of the first example of a nucleoside analogue bearing a 5'-deoxy-beta-D-allo-septanose as a seven-membered ring sugar moiety.

Sizun G, Dukhan D, Griffon JF, Griffe L, Meillon JC, Leroy F, Storer R, Sommadossi JP, Gosselin G. Sizun G, et al. Among authors: leroy f. Carbohydr Res. 2009 Mar 10;344(4):448-53. doi: 10.1016/j.carres.2008.12.019. Epub 2009 Jan 3. Carbohydr Res. 2009. PMID: 19147123

4

Synthesis of 2'-C-methyl-beta-D-ribofuranosylimidazo [4,5-d]-pyridazine derivatives (2-aza-3-deazapurine nucleoside analogues).

Leroy F, Dukhan D, Durka M, Chaves D, Bragnier N, Storer R, Gosselin G. Leroy F, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):667-9. doi: 10.1081/ncn-200060225. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248010

5

Synthesis of 5-aza-7-deazaguanine nucleoside derivatives as potential anti-flavivirus agents.

Dukhan D, Leroy F, Peyronnet J, Bosc E, Chaves D, Durka M, Storer R, La Colla P, Seela F, Gosselin G. Dukhan D, et al. Among authors: leroy f. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):671-4. doi: 10.1081/ncn-200060228. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248011

6

Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease.

Alexandre FR, Brandt G, Caillet C, Chaves D, Convard T, Derock M, Gloux D, Griffon Y, Lallos L, Leroy F, Liuzzi M, Loi AG, Moulat L, Musiu C, Parsy C, Rahali H, Roques V, Seifer M, Standring D, Surleraux D. Alexandre FR, et al. Among authors: leroy f. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3984-91. doi: 10.1016/j.bmcl.2015.07.020. Epub 2015 Jul 14. Bioorg Med Chem Lett. 2015. PMID: 26231161

7

Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.

Pierra Rouvière C, Amador A, Badaroux E, Convard T, Da Costa D, Dukhan D, Griffe L, Griffon JF, LaColla M, Leroy F, Liuzzi M, Loi AG, McCarville J, Mascia V, Milhau J, Onidi L, Paparin JL, Rahali R, Sais E, Seifer M, Surleraux D, Standring D, Dousson C. Pierra Rouvière C, et al. Among authors: leroy f. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4536-4541. doi: 10.1016/j.bmcl.2016.01.042. Epub 2016 Jan 22. Bioorg Med Chem Lett. 2016. PMID: 27520942

8

Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.

Paparin JL, Amador A, Badaroux E, Bot S, Caillet C, Convard T, Da Costa D, Dukhan D, Griffe L, Griffon JF, LaColla M, Leroy F, Liuzzi M, Giulia Loi A, McCarville J, Mascia V, Milhau J, Onidi L, Pierra C, Rahali R, Rosinosky E, Sais E, Seifer M, Surleraux D, Standring D, Dousson CB. Paparin JL, et al. Among authors: leroy f. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2634-2640. doi: 10.1016/j.bmcl.2017.01.017. Epub 2017 Jan 13. Bioorg Med Chem Lett. 2017. PMID: 28416131

9

Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320.

Parsy CC, Alexandre FR, Bidau V, Bonnaterre F, Brandt G, Caillet C, Cappelle S, Chaves D, Convard T, Derock M, Gloux D, Griffon Y, Lallos LB, Leroy F, Liuzzi M, Loi AG, Moulat L, Chiara M, Rahali H, Roques V, Rosinovsky E, Savin S, Seifer M, Standring D, Surleraux D. Parsy CC, et al. Among authors: leroy f. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5427-36. doi: 10.1016/j.bmcl.2015.09.009. Epub 2015 Sep 5. Bioorg Med Chem Lett. 2015. PMID: 26410074

10

Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.

Parsy C, Alexandre FR, Brandt G, Caillet C, Cappelle S, Chaves D, Convard T, Derock M, Gloux D, Griffon Y, Lallos L, Leroy F, Liuzzi M, Loi AG, Moulat L, Musiu C, Rahali H, Roques V, Seifer M, Standring D, Surleraux D. Parsy C, et al. Among authors: leroy f. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4444-4449. doi: 10.1016/j.bmcl.2014.08.002. Epub 2014 Aug 9. Bioorg Med Chem Lett. 2014. PMID: 25155387

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