Yang J - Search Results

1

Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake.

Shang Y, Mao Y, Batson J, Scales SJ, Phillips G, Lackner MR, Totpal K, Williams S, Yang J, Tang Z, Modrusan Z, Tan C, Liang WC, Tsai SP, Vanderbilt A, Kozuka K, Hoeflich K, Tien J, Ross S, Li C, Lee SH, Song A, Wu Y, Stephan JP, Ashkenazi A, Zha J. Shang Y, et al. Among authors: yang j. Mol Cancer Ther. 2008 Sep;7(9):2599-608. doi: 10.1158/1535-7163.MCT-07-2401. Mol Cancer Ther. 2008. PMID: 18790743

2

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.

Junutula JR, Raab H, Clark S, Bhakta S, Leipold DD, Weir S, Chen Y, Simpson M, Tsai SP, Dennis MS, Lu Y, Meng YG, Ng C, Yang J, Lee CC, Duenas E, Gorrell J, Katta V, Kim A, McDorman K, Flagella K, Venook R, Ross S, Spencer SD, Lee Wong W, Lowman HB, Vandlen R, Sliwkowski MX, Scheller RH, Polakis P, Mallet W. Junutula JR, et al. Among authors: yang j. Nat Biotechnol. 2008 Aug;26(8):925-32. doi: 10.1038/nbt.1480. Epub 2008 Jul 20. Nat Biotechnol. 2008. PMID: 18641636

3

A novel homogeneous Biotin-digoxigenin based assay for the detection of human anti-therapeutic antibodies in autoimmune serum.

Qiu ZJ, Ying Y, Fox M, Peng K, Lewin-Koh SC, Coleman D, Good J, Lowe J, Rahman A, Yang J, Jiang J, Quarmby V, Song A. Qiu ZJ, et al. Among authors: yang j. J Immunol Methods. 2010 Oct 31;362(1-2):101-11. doi: 10.1016/j.jim.2010.09.013. Epub 2010 Sep 22. J Immunol Methods. 2010. PMID: 20868690

4

The assay design used for measurement of therapeutic antibody concentrations can affect pharmacokinetic parameters: Case studies.

Fischer SK, Yang J, Anand B, Cowan K, Hendricks R, Li J, Nakamura G, Song A. Fischer SK, et al. Among authors: yang j. MAbs. 2012 Sep-Oct;4(5):623-31. doi: 10.4161/mabs.20814. Epub 2012 Jul 23. MAbs. 2012. PMID: 22820463 Free PMC article.

5

Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies - impact of effector cells.

Chung S, Lin YL, Reed C, Ng C, Cheng ZJ, Malavasi F, Yang J, Quarmby V, Song A. Chung S, et al. Among authors: yang j. J Immunol Methods. 2014 May;407:63-75. doi: 10.1016/j.jim.2014.03.021. Epub 2014 Apr 3. J Immunol Methods. 2014. PMID: 24704820

6

Comparison of binding characteristics and in vitro activities of three inhibitors of vascular endothelial growth factor A.

Yang J, Wang X, Fuh G, Yu L, Wakshull E, Khosraviani M, Day ES, Demeule B, Liu J, Shire SJ, Ferrara N, Yadav S. Yang J, et al. Mol Pharm. 2014 Oct 6;11(10):3421-30. doi: 10.1021/mp500160v. Epub 2014 Sep 16. Mol Pharm. 2014. PMID: 25162961

7

Molecular Interaction Characterization Strategies for the Development of New Biotherapeutic Antibody Modalities.

Wang X, Phan MM, Li J, Gill H, Williams S, Gupta N, Quarmby V, Yang J. Wang X, et al. Among authors: yang j. Antibodies (Basel). 2020 Mar 25;9(2):7. doi: 10.3390/antib9020007. Antibodies (Basel). 2020. PMID: 32218192 Free PMC article.

8

Kelley RF, Yang J, Eigenbrot C, Moran P, Peek M, Lipari MT, Kirchhofer D. Kelley RF, et al. Among authors: yang j. Biochemistry. 2004 Feb 10;43(5):1223-9. doi: 10.1021/bi035738i. Biochemistry. 2004. PMID: 14756558

9

Simple quantitative live cell and anti-idiotypic antibody based ELISA for humanized antibody directed to cell surface protein CD20.

Hong K, Presta LG, Lu Y, Penn A, Adams C, Chuntharapai A, Yang J, Wong WL, Meng YG. Hong K, et al. Among authors: yang j. J Immunol Methods. 2004 Nov;294(1-2):189-97. doi: 10.1016/j.jim.2004.09.003. Epub 2004 Oct 6. J Immunol Methods. 2004. PMID: 15604027

10

Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca fascicularis.

Vugmeyster Y, Beyer J, Howell K, Combs D, Fielder P, Yang J, Qureshi F, Sandlund B, Kawaguchi L, Dummer W, Lowman H, McKeever K. Vugmeyster Y, et al. Among authors: yang j. J Immunother. 2005 May-Jun;28(3):212-9. doi: 10.1097/01.cji.0000155050.03916.04. J Immunother. 2005. PMID: 15838377

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