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Page 1
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger.
Croker BA, Lawson BR, Rutschmann S, Berger M, Eidenschenk C, Blasius AL, Moresco EM, Sovath S, Cengia L, Shultz LD, Theofilopoulos AN, Pettersson S, Beutler BA. Croker BA, et al. Among authors: cengia l. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15028-33. doi: 10.1073/pnas.0806619105. Epub 2008 Sep 19. Proc Natl Acad Sci U S A. 2008. PMID: 18806225 Free PMC article.
Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Speir M, Nowell CJ, Chen AA, O'Donnell JA, Shamie IS, Lakin PR, D'Cruz AA, Braun RO, Babon JJ, Lewis RS, Bliss-Moreau M, Shlomovitz I, Wang S, Cengia LH, Stoica AI, Hakem R, Kelliher MA, O'Reilly LA, Patsiouras H, Lawlor KE, Weller E, Lewis NE, Roberts AW, Gerlic M, Croker BA. Speir M, et al. Among authors: cengia lh. Nat Immunol. 2020 Jan;21(1):54-64. doi: 10.1038/s41590-019-0550-7. Epub 2019 Dec 9. Nat Immunol. 2020. PMID: 31819256 Free PMC article.
Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1.
Croker BA, O'Donnell JA, Nowell CJ, Metcalf D, Dewson G, Campbell KJ, Rogers KL, Hu Y, Smyth GK, Zhang JG, White M, Lackovic K, Cengia LH, O'Reilly LA, Bouillet P, Cory S, Strasser A, Roberts AW. Croker BA, et al. Among authors: cengia lh. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13135-40. doi: 10.1073/pnas.1110358108. Epub 2011 Jul 18. Proc Natl Acad Sci U S A. 2011. PMID: 21768356 Free PMC article.
IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.
Croker BA, Kiu H, Pellegrini M, Toe J, Preston S, Metcalf D, O'Donnell JA, Cengia LH, McArthur K, Nicola NA, Alexander WS, Roberts AW. Croker BA, et al. Among authors: cengia lh. Immunol Cell Biol. 2012 Jan;90(1):124-9. doi: 10.1038/icb.2011.29. Epub 2011 Apr 26. Immunol Cell Biol. 2012. PMID: 21519345 Free PMC article.
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T, Vince JE, Lawlor KE, Ninnis RL, Anderton H, Hall C, Spall SK, Phesse TJ, Abud HE, Cengia LH, Corbin J, Mifsud S, Di Rago L, Metcalf D, Ernst M, Dewson G, Roberts AW, Alexander WS, Murphy JM, Ekert PG, Masters SL, Vaux DL, Croker BA, Gerlic M, Silke J. Rickard JA, et al. Among authors: cengia lh. Cell. 2014 May 22;157(5):1175-88. doi: 10.1016/j.cell.2014.04.019. Epub 2014 May 8. Cell. 2014. PMID: 24813849 Free article.
NLRP1a expression in Srebp-1a-deficient mice.
Gerlic M, Croker BA, Cengia LH, Moayeri M, Kile BT, Masters SL. Gerlic M, et al. Among authors: cengia lh. Cell Metab. 2014 Mar 4;19(3):345-6. doi: 10.1016/j.cmet.2014.02.002. Cell Metab. 2014. PMID: 24606891 Free article. No abstract available.
Fas regulates neutrophil lifespan during viral and bacterial infection.
O'Donnell JA, Kennedy CL, Pellegrini M, Nowell CJ, Zhang JG, O'Reilly LA, Cengia L, Dias S, Masters SL, Hartland EL, Roberts AW, Gerlic M, Croker BA. O'Donnell JA, et al. Among authors: cengia l. J Leukoc Biol. 2015 Feb;97(2):321-6. doi: 10.1189/jlb.3AB1113-594RR. Epub 2014 Dec 3. J Leukoc Biol. 2015. PMID: 25473101
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
Kim ML, Chae JJ, Park YH, De Nardo D, Stirzaker RA, Ko HJ, Tye H, Cengia L, DiRago L, Metcalf D, Roberts AW, Kastner DL, Lew AM, Lyras D, Kile BT, Croker BA, Masters SL. Kim ML, et al. Among authors: cengia l. J Exp Med. 2015 Jun 1;212(6):927-38. doi: 10.1084/jem.20142384. Epub 2015 May 25. J Exp Med. 2015. PMID: 26008898 Free PMC article.
15 results