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Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia.
Río P, Navarro S, Wang W, Sánchez-Domínguez R, Pujol RM, Segovia JC, Bogliolo M, Merino E, Wu N, Salgado R, Lamana ML, Yañez RM, Casado JA, Giménez Y, Román-Rodríguez FJ, Álvarez L, Alberquilla O, Raimbault A, Guenechea G, Lozano ML, Cerrato L, Hernando M, Gálvez E, Hladun R, Giralt I, Barquinero J, Galy A, García de Andoín N, López R, Catalá A, Schwartz JD, Surrallés J, Soulier J, Schmidt M, Díaz de Heredia C, Sevilla J, Bueren JA. Río P, et al. Among authors: alvarez l. Nat Med. 2019 Sep;25(9):1396-1401. doi: 10.1038/s41591-019-0550-z. Epub 2019 Sep 9. Nat Med. 2019. PMID: 31501599 Clinical Trial.
Targeted gene therapy and cell reprogramming in Fanconi anemia.
Rio P, Baños R, Lombardo A, Quintana-Bustamante O, Alvarez L, Garate Z, Genovese P, Almarza E, Valeri A, Díez B, Navarro S, Torres Y, Trujillo JP, Murillas R, Segovia JC, Samper E, Surralles J, Gregory PD, Holmes MC, Naldini L, Bueren JA. Rio P, et al. Among authors: alvarez l. EMBO Mol Med. 2014 Jun;6(6):835-48. doi: 10.15252/emmm.201303374. Epub 2014 Apr 6. EMBO Mol Med. 2014. PMID: 24859981 Free PMC article.
Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients.
Diez B, Genovese P, Roman-Rodriguez FJ, Alvarez L, Schiroli G, Ugalde L, Rodriguez-Perales S, Sevilla J, Diaz de Heredia C, Holmes MC, Lombardo A, Naldini L, Bueren JA, Rio P. Diez B, et al. Among authors: alvarez l. EMBO Mol Med. 2017 Nov;9(11):1574-1588. doi: 10.15252/emmm.201707540. EMBO Mol Med. 2017. PMID: 28899930 Free PMC article.
NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia.
Román-Rodríguez FJ, Ugalde L, Álvarez L, Díez B, Ramírez MJ, Risueño C, Cortón M, Bogliolo M, Bernal S, March F, Ayuso C, Hanenberg H, Sevilla J, Rodríguez-Perales S, Torres-Ruiz R, Surrallés J, Bueren JA, Río P. Román-Rodríguez FJ, et al. Among authors: alvarez l. Cell Stem Cell. 2019 Nov 7;25(5):607-621.e7. doi: 10.1016/j.stem.2019.08.016. Epub 2019 Sep 19. Cell Stem Cell. 2019. PMID: 31543367 Free article.
BCR-JAK2 drives a myeloproliferative neoplasm in transplanted mice.
Cuesta-Domínguez Á, León-Rico D, Álvarez L, Díez B, Bodega-Mayor I, Baños R, Martín-Rey MÁ, Santos-Roncero M, Gaspar ML, Martín-Acosta P, Almarza E, Bueren JA, Río P, Fernández-Ruiz E. Cuesta-Domínguez Á, et al. Among authors: alvarez l. J Pathol. 2015 Jun;236(2):219-28. doi: 10.1002/path.4513. Epub 2015 Mar 3. J Pathol. 2015. PMID: 25664618
Molecular characteristics of atopic dermatitis patients with clinical remission.
Sánchez A, Caraballo A, Alvarez L, Valencia O, Restrepo MN, Gaviria R, Velasquez-Lopera M, Urrego JR, Sánchez J. Sánchez A, et al. Among authors: alvarez l. World Allergy Organ J. 2024 Oct 30;17(11):100983. doi: 10.1016/j.waojou.2024.100983. eCollection 2024 Nov. World Allergy Organ J. 2024. PMID: 39534446 Free PMC article.
Impact of a multifaceted intervention programme on antibiotic prescribing and dispensing in four patient-centred settings in five European countries. The HAPPY PATIENT project.
García-Sangenís A, Lykkegaard J, Hansen MP, González López-Valcárcel B, Raynal F, Vallejo-Torres L, Bjerrum L, Chalkidou A, Jensen JN, Rebnord I, Lindberg BH, Taxis K, Lambert M, Radzeviciene R, Jaruseviciene L, Touboul Lundgren P, Bruno P, Lesage V, Kowalczyk A, Godycki-Cwirko M, Lionis C, Karkana MN, Anastasaki M, Hansen MB, Olsen JK, Søndergaard J, Modena D, Mally S, Álvarez L, Llor C. García-Sangenís A, et al. Among authors: alvarez l. Fam Pract. 2024 Nov 12:cmae064. doi: 10.1093/fampra/cmae064. Online ahead of print. Fam Pract. 2024. PMID: 39531344
1,533 results