Kirkpatrick C - Search Results

1

Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells.

Park KS, Wiederkehr A, Kirkpatrick C, Mattenberger Y, Martinou JC, Marchetti P, Demaurex N, Wollheim CB. Park KS, et al. Among authors: kirkpatrick c. J Biol Chem. 2008 Nov 28;283(48):33347-56. doi: 10.1074/jbc.M806251200. Epub 2008 Oct 2. J Biol Chem. 2008. PMID: 18832378 Free PMC article.

2

Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.

Pongratz RL, Kibbey RG, Kirkpatrick CL, Zhao X, Pontoglio M, Yaniv M, Wollheim CB, Shulman GI, Cline GW. Pongratz RL, et al. J Biol Chem. 2009 Jun 19;284(25):16808-16821. doi: 10.1074/jbc.M807723200. Epub 2009 Apr 17. J Biol Chem. 2009. PMID: 19376774 Free PMC article.

3

Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress.

Kirkpatrick CL, Wiederkehr A, Baquié M, Akhmedov D, Wang H, Gauthier BR, Akerman I, Ishihara H, Ferrer J, Wollheim CB. Kirkpatrick CL, et al. J Biol Chem. 2011 Sep 16;286(37):32300-12. doi: 10.1074/jbc.M111.247866. Epub 2011 Jul 22. J Biol Chem. 2011. PMID: 21784843 Free PMC article.

4

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.

Dayeh T, Volkov P, Salö S, Hall E, Nilsson E, Olsson AH, Kirkpatrick CL, Wollheim CB, Eliasson L, Rönn T, Bacos K, Ling C. Dayeh T, et al. Among authors: kirkpatrick cl. PLoS Genet. 2014 Mar 6;10(3):e1004160. doi: 10.1371/journal.pgen.1004160. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24603685 Free PMC article.

5

Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.

Kirkpatrick CL, Marchetti P, Purrello F, Piro S, Bugliani M, Bosco D, de Koning EJ, Engelse MA, Kerr-Conte J, Pattou F, Wollheim CB. Kirkpatrick CL, et al. PLoS One. 2010 Jun 10;5(6):e11053. doi: 10.1371/journal.pone.0011053. PLoS One. 2010. PMID: 20548773 Free PMC article.

6

Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells.

Epstein S, Kirkpatrick CL, Castillon GA, Muñiz M, Riezman I, David FPA, Wollheim CB, Riezman H. Epstein S, et al. J Lipid Res. 2012 Mar;53(3):412-420. doi: 10.1194/jlr.M022186. Epub 2011 Dec 30. J Lipid Res. 2012. PMID: 22210926 Free PMC article.

7

Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.

Bugliani M, Liechti R, Cheon H, Suleiman M, Marselli L, Kirkpatrick C, Filipponi F, Boggi U, Xenarios I, Syed F, Ladriere L, Wollheim C, Lee MS, Marchetti P. Bugliani M, et al. Among authors: kirkpatrick c. Mol Cell Endocrinol. 2013 Mar 10;367(1-2):1-10. doi: 10.1016/j.mce.2012.12.001. Epub 2012 Dec 12. Mol Cell Endocrinol. 2013. PMID: 23246353

8

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.

Marchetti P, Lupi R, Bugliani M, Kirkpatrick CL, Sebastiani G, Grieco FA, Del Guerra S, D'Aleo V, Piro S, Marselli L, Boggi U, Filipponi F, Tinti L, Salvini L, Wollheim CB, Purrello F, Dotta F. Marchetti P, et al. Among authors: kirkpatrick cl. Diabetologia. 2012 Dec;55(12):3262-72. doi: 10.1007/s00125-012-2716-9. Epub 2012 Sep 11. Diabetologia. 2012. PMID: 22965295

9

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets.

Yang BT, Dayeh TA, Kirkpatrick CL, Taneera J, Kumar R, Groop L, Wollheim CB, Nitert MD, Ling C. Yang BT, et al. Among authors: kirkpatrick cl. Diabetologia. 2011 Feb;54(2):360-7. doi: 10.1007/s00125-010-1967-6. Epub 2010 Nov 23. Diabetologia. 2011. PMID: 21104225 Free PMC article.

10

Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes.

Yang BT, Dayeh TA, Volkov PA, Kirkpatrick CL, Malmgren S, Jing X, Renström E, Wollheim CB, Nitert MD, Ling C. Yang BT, et al. Among authors: kirkpatrick cl. Mol Endocrinol. 2012 Jul;26(7):1203-12. doi: 10.1210/me.2012-1004. Epub 2012 May 8. Mol Endocrinol. 2012. PMID: 22570331 Free PMC article.

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