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Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function.
Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD. Lavine JA, et al. Mol Endocrinol. 2008 Dec;22(12):2716-28. doi: 10.1210/me.2008-0255. Epub 2008 Oct 9. Mol Endocrinol. 2008. Retraction in: Mol Endocrinol. 2010 Feb;24(2):472. doi: 10.1210/mend.24.2.9999 PMID: 18845673 Free PMC article. Retracted.
FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.
Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. Davis DB, et al. Among authors: lavine ja. Mol Endocrinol. 2010 Sep;24(9):1822-34. doi: 10.1210/me.2010-0082. Epub 2010 Jul 21. Mol Endocrinol. 2010. PMID: 20660304 Free PMC article.
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.
Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB. Krautkramer KA, et al. Among authors: lavine ja. Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E600-10. doi: 10.1152/ajpendo.00147.2013. Epub 2013 Jul 16. Am J Physiol Endocrinol Metab. 2013. PMID: 23860123 Free PMC article.
Cholecystokinin expression in the β-cell leads to increased β-cell area in aged mice and protects from streptozotocin-induced diabetes and apoptosis.
Lavine JA, Kibbe CR, Baan M, Sirinvaravong S, Umhoefer HM, Engler KA, Meske LM, Sacotte KA, Erhardt DP, Davis DB. Lavine JA, et al. Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E819-28. doi: 10.1152/ajpendo.00159.2015. Epub 2015 Sep 22. Am J Physiol Endocrinol Metab. 2015. PMID: 26394663 Free PMC article.
50 results