Boyd M - Search Results

1

Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid.

Rewcastle GW, Atwell GJ, Baguley BC, Boyd M, Thomsen LL, Zhuang L, Denny WA. Rewcastle GW, et al. Among authors: boyd m. J Med Chem. 1991 Sep;34(9):2864-70. doi: 10.1021/jm00113a027. J Med Chem. 1991. PMID: 1895304

2

Hypoxia-activated prodrugs: substituent effects on the properties of nitro seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (nitroCBI) prodrugs of DNA minor groove alkylating agents.

Tercel M, Atwell GJ, Yang S, Stevenson RJ, Botting KJ, Boyd M, Smith E, Anderson RF, Denny WA, Wilson WR, Pruijn FB. Tercel M, et al. Among authors: boyd m. J Med Chem. 2009 Nov 26;52(22):7258-72. doi: 10.1021/jm901202b. J Med Chem. 2009. PMID: 19877646

3

Potential antitumor agents. 64. Synthesis and antitumor evaluation of dibenzo[1,4]dioxin-1-carboxamides: a new class of weakly binding DNA-intercalating agents.

Lee HH, Palmer BD, Boyd M, Baguley BC, Denny WA. Lee HH, et al. Among authors: boyd m. J Med Chem. 1992 Jan 24;35(2):258-66. doi: 10.1021/jm00080a009. J Med Chem. 1992. PMID: 1310119

4

Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins.

Denny WA, Atwell GJ, Roberts PB, Anderson RF, Boyd M, Lock CJ, Wilson WR. Denny WA, et al. Among authors: boyd m. J Med Chem. 1992 Dec 25;35(26):4832-41. doi: 10.1021/jm00104a008. J Med Chem. 1992. PMID: 1479583

5

NMR studies of configuration and tautomeric equilibria in nitroacridine antitumor agents.

Boyd M, Denny WA. Boyd M, et al. J Med Chem. 1990 Sep;33(9):2656-9. doi: 10.1021/jm00171a049. J Med Chem. 1990. PMID: 2391704

6

Synthesis, DNA interactions and biological activity of DNA minor groove targeted polybenzamide-linked nitrogen mustards.

Atwell GJ, Yaghi BM, Turner PR, Boyd M, O'Connor CJ, Ferguson LR, Baguley BC, Denny WA. Atwell GJ, et al. Among authors: boyd m. Bioorg Med Chem. 1995 Jun;3(6):679-91. doi: 10.1016/0968-0896(95)00049-m. Bioorg Med Chem. 1995. PMID: 7582946

7

Tyrosine kinase inhibitors. 4. Structure-activity relationships among N- and 3-substituted 2,2'-dithiobis(1H-indoles) for in vitro inhibition of receptor and nonreceptor protein tyrosine kinases.

Palmer BD, Rewcastle GW, Thompson AM, Boyd M, Showalter HD, Sercel AD, Fry DW, Kraker AJ, Denny WA. Palmer BD, et al. Among authors: boyd m. J Med Chem. 1995 Jan 6;38(1):58-67. doi: 10.1021/jm00001a011. J Med Chem. 1995. PMID: 7837241

8

Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.

Palmer BD, Wilson WR, Anderson RF, Boyd M, Denny WA. Palmer BD, et al. Among authors: boyd m. J Med Chem. 1996 Jun 21;39(13):2518-28. doi: 10.1021/jm960057p. J Med Chem. 1996. PMID: 8691449

9

Pyrazole analogues of the bispyrrolecarboxamide anti-tumour antibiotics: synthesis, DNA binding and anti-tumour properties.

Lee HH, Boyd M, Gravatt GL, Denny WA. Lee HH, et al. Among authors: boyd m. Anticancer Drug Des. 1991 Nov;6(5):501-17. Anticancer Drug Des. 1991. PMID: 1662514

10

Synthesis and evaluation of 4-substituted analogues of 5-[N,N-bis (2-chloroethyl)amino]-2-nitrobenzamide as bioreductively activated prodrugs using an Escherichia coli nitroreductase.

Atwell GJ, Boyd M, Palmer BD, Anderson RF, Pullen SM, Wilson WR, Denny WA. Atwell GJ, et al. Among authors: boyd m. Anticancer Drug Des. 1996 Oct;11(7):553-67. Anticancer Drug Des. 1996. PMID: 8921936

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