Ambudkar SV - Search Results

1

Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2.

Shukla S, Robey RW, Bates SE, Ambudkar SV. Shukla S, et al. Among authors: ambudkar sv. Drug Metab Dispos. 2009 Feb;37(2):359-65. doi: 10.1124/dmd.108.024612. Epub 2008 Oct 29. Drug Metab Dispos. 2009. PMID: 18971320 Free PMC article.

2

Heterologous expression systems for P-glycoprotein: E. coli, yeast, and baculovirus.

Evans GL, Ni B, Hrycyna CA, Chen D, Ambudkar SV, Pastan I, Germann UA, Gottesman MM. Evans GL, et al. Among authors: ambudkar sv. J Bioenerg Biomembr. 1995 Feb;27(1):43-52. doi: 10.1007/BF02110330. J Bioenerg Biomembr. 1995. PMID: 7629051 Review.

3

Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells.

Germann UA, Chambers TC, Ambudkar SV, Licht T, Cardarelli CO, Pastan I, Gottesman MM. Germann UA, et al. Among authors: ambudkar sv. J Biol Chem. 1996 Jan 19;271(3):1708-16. doi: 10.1074/jbc.271.3.1708. J Biol Chem. 1996. PMID: 8576173 Free article.

4

Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.

Ramachandra M, Ambudkar SV, Gottesman MM, Pastan I, Hrycyna CA. Ramachandra M, et al. Among authors: ambudkar sv. Mol Biol Cell. 1996 Oct;7(10):1485-98. doi: 10.1091/mbc.7.10.1485. Mol Biol Cell. 1996. PMID: 8898356 Free PMC article.

5

P-glycoprotein and multidrug resistance.

Gottesman MM, Pastan I, Ambudkar SV. Gottesman MM, et al. Among authors: ambudkar sv. Curr Opin Genet Dev. 1996 Oct;6(5):610-7. doi: 10.1016/s0959-437x(96)80091-8. Curr Opin Genet Dev. 1996. PMID: 8939727 Review.

6

Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein.

Ambudkar SV, Cardarelli CO, Pashinsky I, Stein WD. Ambudkar SV, et al. J Biol Chem. 1997 Aug 22;272(34):21160-6. doi: 10.1074/jbc.272.34.21160. J Biol Chem. 1997. PMID: 9261121 Free article.

7

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein.

Dey S, Ramachandra M, Pastan I, Gottesman MM, Ambudkar SV. Dey S, et al. Among authors: ambudkar sv. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10594-9. doi: 10.1073/pnas.94.20.10594. Proc Natl Acad Sci U S A. 1997. PMID: 9380680 Free PMC article.

8

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

Lee CG, Gottesman MM, Cardarelli CO, Ramachandra M, Jeang KT, Ambudkar SV, Pastan I, Dey S. Lee CG, et al. Among authors: ambudkar sv. Biochemistry. 1998 Mar 17;37(11):3594-601. doi: 10.1021/bi972709x. Biochemistry. 1998. PMID: 9530286

9

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state.

Ramachandra M, Ambudkar SV, Chen D, Hrycyna CA, Dey S, Gottesman MM, Pastan I. Ramachandra M, et al. Among authors: ambudkar sv. Biochemistry. 1998 Apr 7;37(14):5010-9. doi: 10.1021/bi973045u. Biochemistry. 1998. PMID: 9538020

10

Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites.

Hrycyna CA, Ramachandra M, Ambudkar SV, Ko YH, Pedersen PL, Pastan I, Gottesman MM. Hrycyna CA, et al. Among authors: ambudkar sv. J Biol Chem. 1998 Jul 3;273(27):16631-4. doi: 10.1074/jbc.273.27.16631. J Biol Chem. 1998. PMID: 9642211 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

304 results

Search Page

Filters