Polin LA - Search Results

1

The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms.

Risinger AL, Jackson EM, Polin LA, Helms GL, LeBoeuf DA, Joe PA, Hopper-Borge E, Ludueña RF, Kruh GD, Mooberry SL. Risinger AL, et al. Among authors: polin la. Cancer Res. 2008 Nov 1;68(21):8881-8. doi: 10.1158/0008-5472.CAN-08-2037. Cancer Res. 2008. PMID: 18974132 Free PMC article.

2

CB694, a novel antimitotic with antitumor activities.

Weiderhold KN, Randall-Hlubek DA, Polin LA, Hamel E, Mooberry SL. Weiderhold KN, et al. Among authors: polin la. Int J Cancer. 2006 Feb 15;118(4):1032-40. doi: 10.1002/ijc.21424. Int J Cancer. 2006. PMID: 16152590

3

Identification and biological activities of new taccalonolide microtubule stabilizers.

Peng J, Risinger AL, Fest GA, Jackson EM, Helms G, Polin LA, Mooberry SL. Peng J, et al. Among authors: polin la. J Med Chem. 2011 Sep 8;54(17):6117-24. doi: 10.1021/jm200757g. Epub 2011 Aug 11. J Med Chem. 2011. PMID: 21800839 Free PMC article.

4

Antitumor efficacy of PD115934 (NSC 366140) against solid tumors of mice.

LoRusso P, Wozniak AJ, Polin L, Capps D, Leopold WR, Werbel LM, Biernat L, Dan ME, Corbett TH. LoRusso P, et al. Cancer Res. 1990 Aug 15;50(16):4900-5. Cancer Res. 1990. PMID: 2165850

5

Biological evaluation of cryptophycin 52 fragment A analogues: effect of the multidrug resistance ATP binding cassette transporters on antitumor activity.

Al-Awar RS, Corbett TH, Ray JE, Polin L, Kennedy JH, Wagner MM, Williams DC. Al-Awar RS, et al. Mol Cancer Ther. 2004 Sep;3(9):1061-7. Mol Cancer Ther. 2004. PMID: 15367700

6

ONC201 induces the unfolded protein response (UPR) in high- and low-grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity.

Rumman M, Buck S, Polin L, Dzinic S, Boerner J, Winer IS. Rumman M, et al. Cancer Med. 2021 May;10(10):3373-3387. doi: 10.1002/cam4.3858. Epub 2021 May 1. Cancer Med. 2021. PMID: 33932119 Free PMC article.

7

Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, Paluch J, White K, Edelstein M, Palomino E, Corbett TH, Horwitz JP. Hazeldine ST, et al. J Med Chem. 2001 May 24;44(11):1758-76. doi: 10.1021/jm0005149. J Med Chem. 2001. PMID: 11356111

8

II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, White K, Bouregeois NM, Crantz B, Palomino E, Corbett TH, Horwitz JP. Hazeldine ST, et al. J Med Chem. 2002 Jul 4;45(14):3130-7. doi: 10.1021/jm0200097. J Med Chem. 2002. PMID: 12086498

9

Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP. Hazeldine ST, et al. Bioorg Med Chem. 2006 Apr 1;14(7):2462-7. doi: 10.1016/j.bmc.2005.11.036. Epub 2005 Dec 5. Bioorg Med Chem. 2006. PMID: 16337128

10

Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase.

Wang L, Desmoulin SK, Cherian C, Polin L, White K, Kushner J, Fulterer A, Chang MH, Mitchell-Ryan S, Stout M, Romero MF, Hou Z, Matherly LH, Gangjee A. Wang L, et al. J Med Chem. 2011 Oct 27;54(20):7150-64. doi: 10.1021/jm200739e. Epub 2011 Sep 22. J Med Chem. 2011. PMID: 21879757 Free PMC article.

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