McCarthy MI - Search Results

1

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, Li M, Derohannessian S, de Bakker PI, Bailey SD, Montpetit A, Edmondson AC, Taylor K, Gai X, Wang SS, Fornage M, Shaikh T, Groop L, Boehnke M, Hall AS, Hattersley AT, Frackelton E, Patterson N, Chiang CW, Kim CE, Fabsitz RR, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W, McCarthy MI, Kathiresan S, Gabriel SB, Hakonarson H, Anand SS, Reilly M, Engert JC, Nickerson DA, Rader DJ, Hirschhorn JN, Fitzgerald GA. Keating BJ, et al. Among authors: mccarthy mi. PLoS One. 2008;3(10):e3583. doi: 10.1371/journal.pone.0003583. Epub 2008 Oct 31. PLoS One. 2008. PMID: 18974833 Free PMC article.

2

Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset.

Zeggini E, Parkinson J, Halford S, Owen KR, Frayling TM, Walker M, Hitman GA, Levy JC, Sampson MJ, Feskens EJ, Hattersley AT, McCarthy MI. Zeggini E, et al. Among authors: mccarthy mi. Diabetes. 2004 Dec;53(12):3319-22. doi: 10.2337/diabetes.53.12.3319. Diabetes. 2004. PMID: 15561966

3

A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.

Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Hattersley AT, Frayling TM. Weedon MN, et al. Among authors: mccarthy mi. Diabetes. 2005 Aug;54(8):2487-91. doi: 10.2337/diabetes.54.8.2487. Diabetes. 2005. PMID: 16046319

4

What makes a good genetic association study?

Hattersley AT, McCarthy MI. Hattersley AT, et al. Among authors: mccarthy mi. Lancet. 2005 Oct 8;366(9493):1315-23. doi: 10.1016/S0140-6736(05)67531-9. Lancet. 2005. PMID: 16214603

5

An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets.

Zeggini E, Rayner W, Morris AP, Hattersley AT, Walker M, Hitman GA, Deloukas P, Cardon LR, McCarthy MI. Zeggini E, et al. Among authors: mccarthy mi. Nat Genet. 2005 Dec;37(12):1320-2. doi: 10.1038/ng1670. Epub 2005 Oct 30. Nat Genet. 2005. PMID: 16258542

6

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people.

Florez JC, Wiltshire S, Agapakis CM, Burtt NP, de Bakker PI, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, McCarthy MI, Altshuler D, Groop L. Florez JC, et al. Among authors: mccarthy mi. Diabetes. 2006 Jan;55(1):128-35. Diabetes. 2006. PMID: 16380485

7

Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.

Freathy RM, Weedon MN, Shields B, Hitman GA, Walker M, McCarthy MI, Hattersley AT, Frayling TM. Freathy RM, et al. Among authors: mccarthy mi. JOP. 2006 May 9;7(3):295-302. JOP. 2006. PMID: 16685110

8

Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.

Groves CJ, Zeggini E, Walker M, Hitman GA, Levy JC, O'Rahilly S, Hattersley AT, McCarthy MI, Wiltshire S. Groves CJ, et al. Among authors: mccarthy mi. Diabetes. 2006 Jun;55(6):1884-9. doi: 10.2337/db05-1674. Diabetes. 2006. PMID: 16731858

9

The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians.

Freathy RM, Weedon MN, Melzer D, Shields B, Hitman GA, Walker M, McCarthy MI, Hattersley AT, Frayling TM. Freathy RM, et al. Among authors: mccarthy mi. BMC Med Genet. 2006 Jun 5;7:51. doi: 10.1186/1471-2350-7-51. BMC Med Genet. 2006. PMID: 16753056 Free PMC article.

10

Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach.

Gloyn AL, Mackay DJ, Weedon MN, McCarthy MI, Walker M, Hitman G, Knight BA, Owen KR, Hattersley AT, Frayling TM. Gloyn AL, et al. Among authors: mccarthy mi. Diabetes. 2006 Aug;55(8):2272-6. doi: 10.2337/db06-0216. Diabetes. 2006. PMID: 16873690

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