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Advances in high-throughput methodologies for crystallizing proteins.
Chamberlain PP, Klock HE, McMullan D, DiDonato M, Kreusch A, Lesley SA, Spraggon G. Chamberlain PP, et al. Among authors: lesley sa. Biotechnol Genet Eng Rev. 2006;23:1-19. doi: 10.1080/02648725.2006.10648075. Biotechnol Genet Eng Rev. 2006. PMID: 22530499 Review. No abstract available.
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline.
Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Lesley SA, et al. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. doi: 10.1073/pnas.142413399. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193646 Free PMC article.
Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase.
Kreusch A, Spraggon G, Lee CC, Klock H, McMullan D, Ng K, Shin T, Vincent J, Warner I, Ericson C, Lesley SA. Kreusch A, et al. Among authors: lesley sa. J Mol Biol. 2003 Jul 4;330(2):309-21. doi: 10.1016/s0022-2836(03)00596-5. J Mol Biol. 2003. PMID: 12823970
High-throughput protein production for X-ray crystallography and use of size exclusion chromatography to validate or refute computational biological unit predictions.
McMullan D, Canaves JM, Quijano K, Abdubek P, Nigoghossian E, Haugen J, Klock HE, Vincent J, Hale J, Paulsen J, Lesley SA. McMullan D, et al. Among authors: lesley sa. J Struct Funct Genomics. 2005;6(2-3):135-41. doi: 10.1007/s10969-005-2898-1. J Struct Funct Genomics. 2005. PMID: 16211510
A structural basis for the regulatory inactivation of DnaA.
Xu Q, McMullan D, Abdubek P, Astakhova T, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Elsliger MA, Feuerhelm J, Hale J, Han GW, Jaroszewski L, Jin KK, Johnson HA, Klock HE, Knuth MW, Kozbial P, Sri Krishna S, Kumar A, Marciano D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L, Oommachen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Trame C, van den Bedem H, Weekes D, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA. Xu Q, et al. Among authors: lesley sa. J Mol Biol. 2009 Jan 16;385(2):368-80. doi: 10.1016/j.jmb.2008.10.059. Epub 2008 Oct 30. J Mol Biol. 2009. PMID: 19000695 Free PMC article.
208 results