Smyth MJ - Search Results

1

Dihydrofuro[3,4-c]pyridinones as inhibitors of the cytolytic effects of the pore-forming glycoprotein perforin.

Lena G, Trapani JA, Sutton VR, Ciccone A, Browne KA, Smyth MJ, Denny WA, Spicer JA. Lena G, et al. Among authors: smyth mj. J Med Chem. 2008 Dec 11;51(23):7614-24. doi: 10.1021/jm801063n. J Med Chem. 2008. PMID: 19007200

2

Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia.

Smyth MJ, Wiltrout T, Trapani JA, Ottaway KS, Sowder R, Henderson LE, Kam CM, Powers JC, Young HA, Sayers TJ. Smyth MJ, et al. J Biol Chem. 1992 Dec 5;267(34):24418-25. J Biol Chem. 1992. PMID: 1447189 Free article.

3

Distinct granzyme expression in human CD3- CD56+ large granular- and CD3- CD56+ small high density-lymphocytes displaying non-MHC-restricted cytolytic activity.

Smyth MJ, Browne KA, Kinnear BF, Trapani JA, Warren HS. Smyth MJ, et al. J Leukoc Biol. 1995 Jan;57(1):88-93. doi: 10.1002/jlb.57.1.88. J Leukoc Biol. 1995. PMID: 7530284

4

The peptide loop consisting of amino acids 139-157 of human granzyme B (fragmentin 2) contains an immunodominant epitope recognized by the mouse.

Apostolidis VA, Browne KA, Smyth MJ, Trapani JA. Apostolidis VA, et al. Among authors: smyth mj. Mol Immunol. 1995 Aug;32(12):909-17. doi: 10.1016/0161-5890(95)00042-d. Mol Immunol. 1995. PMID: 7565817

5

Cloning and characterization of a novel NK cell-specific serine protease gene and its functional 5'-flanking sequences.

Smyth MJ, Hulett MD, Thia KY, Young HA, Sayers TJ, Carter CR, Trapani JA. Smyth MJ, et al. Immunogenetics. 1995;42(2):101-11. doi: 10.1007/BF00178584. Immunogenetics. 1995. PMID: 7607701

6

Granzymes: exogenous proteinases that induce target cell apoptosis.

Smyth MJ, Trapani JA. Smyth MJ, et al. Immunol Today. 1995 Apr;16(4):202-6. doi: 10.1016/0167-5699(95)80122-7. Immunol Today. 1995. PMID: 7734049 Review.

7

Granule serine proteases are normal nuclear constituents of natural killer cells.

Trapani JA, Smyth MJ, Apostolidis VA, Dawson M, Browne KA. Trapani JA, et al. Among authors: smyth mj. J Biol Chem. 1994 Jul 15;269(28):18359-65. J Biol Chem. 1994. PMID: 8034581 Free article.

8

Use of the 5'-flanking region of the mouse perforin gene to express human Fc gamma receptor I in cytotoxic T lymphocytes.

Smyth MJ, Kershaw MH, Hulett MD, McKenzie IF, Trapani JA. Smyth MJ, et al. J Leukoc Biol. 1994 Apr;55(4):514-22. doi: 10.1002/jlb.55.4.514. J Leukoc Biol. 1994. PMID: 8145022

9

Hypothesis: cytotoxic lymphocyte granule serine proteases activate target cell endonucleases to trigger apoptosis.

Smyth MJ, Browne KA, Thia KY, Apostolidis VA, Kershaw MH, Trapani JA. Smyth MJ, et al. Clin Exp Pharmacol Physiol. 1994 Jan;21(1):67-70. doi: 10.1111/j.1440-1681.1994.tb02438.x. Clin Exp Pharmacol Physiol. 1994. PMID: 8156655

10

Met-ase: cloning and distinct chromosomal location of a serine protease preferentially expressed in human natural killer cells.

Smyth MJ, Sayers TJ, Wiltrout T, Powers JC, Trapani JA. Smyth MJ, et al. J Immunol. 1993 Dec 1;151(11):6195-205. J Immunol. 1993. PMID: 8245461

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