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Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, Sessa WC, Dvorak HF, Benjamin LE. Phung TL, et al. Among authors: dvorak hf, dvorak am. Cancer Cell. 2006 Aug;10(2):159-70. doi: 10.1016/j.ccr.2006.07.003. Cancer Cell. 2006. PMID: 16904613 Free PMC article.
VEGF-A and the induction of pathological angiogenesis.
Nagy JA, Dvorak AM, Dvorak HF. Nagy JA, et al. Among authors: dvorak hf, dvorak am. Annu Rev Pathol. 2007;2:251-75. doi: 10.1146/annurev.pathol.2.010506.134925. Annu Rev Pathol. 2007. PMID: 18039100 Review.
Vascular permeability, vascular hyperpermeability and angiogenesis.
Nagy JA, Benjamin L, Zeng H, Dvorak AM, Dvorak HF. Nagy JA, et al. Among authors: dvorak hf, dvorak am. Angiogenesis. 2008;11(2):109-19. doi: 10.1007/s10456-008-9099-z. Epub 2008 Feb 22. Angiogenesis. 2008. PMID: 18293091 Free PMC article. Review.
VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation.
Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. Chang SH, et al. Among authors: dvorak hf. Cancer Res. 2009 May 15;69(10):4537-44. doi: 10.1158/0008-5472.CAN-08-4539. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435903 Free PMC article.
315 results