Kamenecka TM - Search Results

1

Insular hypocretin transmission regulates nicotine reward.

Hollander JA, Lu Q, Cameron MD, Kamenecka TM, Kenny PJ. Hollander JA, et al. Among authors: kamenecka tm. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19480-5. doi: 10.1073/pnas.0808023105. Epub 2008 Nov 24. Proc Natl Acad Sci U S A. 2008. PMID: 19033203 Free PMC article.

2

Bioactivation of the epidermal growth factor receptor inhibitor gefitinib: implications for pulmonary and hepatic toxicities.

Li X, Kamenecka TM, Cameron MD. Li X, et al. Among authors: kamenecka tm. Chem Res Toxicol. 2009 Oct;22(10):1736-42. doi: 10.1021/tx900256y. Chem Res Toxicol. 2009. PMID: 19803472

3

Synthesis, biological evaluation, X-ray structure, and pharmacokinetics of aminopyrimidine c-jun-N-terminal kinase (JNK) inhibitors.

Kamenecka T, Jiang R, Song X, Duckett D, Chen W, Ling YY, Habel J, Laughlin JD, Chambers J, Figuera-Losada M, Cameron MD, Lin L, Ruiz CH, LoGrasso PV. Kamenecka T, et al. J Med Chem. 2010 Jan 14;53(1):419-31. doi: 10.1021/jm901351f. J Med Chem. 2010. PMID: 19947601 Free PMC article.

4

Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile.

Li X, Kamenecka TM, Cameron MD. Li X, et al. Among authors: kamenecka tm. Drug Metab Dispos. 2010 Jul;38(7):1238-45. doi: 10.1124/dmd.109.030361. Epub 2010 Apr 9. Drug Metab Dispos. 2010. PMID: 20382753 Free PMC article.

5

Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors.

Noël R, Shin Y, Song X, He Y, Koenig M, Chen W, Ling YY, Lin L, Ruiz CH, LoGrasso P, Cameron MD, Duckett DR, Kamenecka TM. Noël R, et al. Among authors: kamenecka tm. Bioorg Med Chem Lett. 2011 May 1;21(9):2732-5. doi: 10.1016/j.bmcl.2010.11.104. Epub 2010 Dec 1. Bioorg Med Chem Lett. 2011. PMID: 21185177 Free PMC article.

6

Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) inhibitors.

He Y, Kamenecka TM, Shin Y, Song X, Jiang R, Noel R, Duckett D, Chen W, Ling YY, Cameron MD, Lin L, Khan S, Koenig M, LoGrasso PV. He Y, et al. Among authors: kamenecka tm. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1719-23. doi: 10.1016/j.bmcl.2011.01.079. Epub 2011 Jan 22. Bioorg Med Chem Lett. 2011. PMID: 21316221 Free PMC article.

7

Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptors.

Busby SA, Kumar N, Kuruvilla DS, Istrate MA, Conkright JJ, Wang Y, Kamenecka TM, Cameron MD, Roush WR, Burris TP, Griffin PR. Busby SA, et al. Among authors: kamenecka tm. ACS Chem Biol. 2011 Jun 17;6(6):618-27. doi: 10.1021/cb100396s. Epub 2011 Mar 17. ACS Chem Biol. 2011. PMID: 21381756 Free PMC article.

8

Small Molecule c-jun-N-terminal Kinase (JNK) Inhibitors Protect Dopaminergic Neurons in a Model of Parkinson's Disease.

Chambers JW, Pachori A, Howard S, Ganno M, Hansen D Jr, Kamenecka T, Song X, Duckett D, Chen W, Ling YY, Cherry L, Cameron MD, Lin L, Ruiz CH, Lograsso P. Chambers JW, et al. ACS Chem Neurosci. 2011 Apr 20;2(4):198-206. doi: 10.1021/cn100109k. ACS Chem Neurosci. 2011. PMID: 21666839 Free PMC article.

9

Synthesis and SAR of 2-phenoxypyridines as novel c-Jun N-terminal kinase inhibitors.

Song X, Chen W, Lin L, Ruiz CH, Cameron MD, Duckett DR, Kamenecka TM. Song X, et al. Among authors: kamenecka tm. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7072-5. doi: 10.1016/j.bmcl.2011.09.090. Epub 2011 Sep 29. Bioorg Med Chem Lett. 2011. PMID: 22004719

10

Imidazopyridines as selective CYP3A4 inhibitors.

Song X, Li X, Ruiz CH, Yin Y, Feng Y, Kamenecka TM, Cameron MD. Song X, et al. Among authors: kamenecka tm. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1611-4. doi: 10.1016/j.bmcl.2011.12.125. Epub 2012 Jan 4. Bioorg Med Chem Lett. 2012. PMID: 22264486 Free PMC article.

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