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Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation.
Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ. Cortez-Retamozo V, et al. Among authors: blois j. J Clin Invest. 2008 Dec;118(12):4058-66. doi: 10.1172/JCI36335. Epub 2008 Nov 6. J Clin Invest. 2008. PMID: 19033674 Free PMC article.
Slow self-activation enhances the potency of viridin prodrugs.
Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L. Blois J, et al. J Med Chem. 2008 Aug 14;51(15):4699-707. doi: 10.1021/jm800374f. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630894 Free PMC article.
The antiproliferative cytostatic effects of a self-activating viridin prodrug.
Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L. Smith A, et al. Among authors: blois j. Mol Cancer Ther. 2009 Jun;8(6):1666-75. doi: 10.1158/1535-7163.MCT-08-1012. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509266 Free PMC article.
Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.
Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Stangenberg L, et al. Among authors: blois j. Arthritis Rheum. 2009 Aug;60(8):2314-24. doi: 10.1002/art.24704. Arthritis Rheum. 2009. PMID: 19644878 Free PMC article.
A stabilized demethoxyviridin derivative inhibits PI3 kinase.
Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L. Yuan H, et al. Among authors: blois j. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4223-7. doi: 10.1016/j.bmcl.2009.05.105. Epub 2009 May 30. Bioorg Med Chem Lett. 2009. PMID: 19523825 Free PMC article.
Fate of a bioactive fluorescent wortmannin derivative in cells.
Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L. Barnes KR, et al. Among authors: blois j. Bioconjug Chem. 2008 Jan;19(1):130-7. doi: 10.1021/bc7002204. Epub 2007 Nov 8. Bioconjug Chem. 2008. PMID: 17988080
A DNA-binding Gd chelate for the detection of cell death by MRI.
Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L. Garanger E, et al. Chem Commun (Camb). 2009 Aug 7;(29):4444-6. doi: 10.1039/b907375b. Epub 2009 Jun 12. Chem Commun (Camb). 2009. PMID: 19597620 Free PMC article.
48 results