Heidel JD - Search Results

1

Targeted delivery of siRNA to cell death proteins in sepsis.

Brahmamdam P, Watanabe E, Unsinger J, Chang KC, Schierding W, Hoekzema AS, Zhou TT, McDonough JS, Holemon H, Heidel JD, Coopersmith CM, McDunn JE, Hotchkiss RS. Brahmamdam P, et al. Among authors: heidel jd. Shock. 2009 Aug;32(2):131-9. doi: 10.1097/SHK.0b013e318194bcee. Shock. 2009. PMID: 19033888 Free PMC article.

2

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles.

Davis ME, Zuckerman JE, Choi CH, Seligson D, Tolcher A, Alabi CA, Yen Y, Heidel JD, Ribas A. Davis ME, et al. Among authors: heidel jd. Nature. 2010 Apr 15;464(7291):1067-70. doi: 10.1038/nature08956. Epub 2010 Mar 21. Nature. 2010. PMID: 20305636 Free PMC article.

3

Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma.

Hu-Lieskovan S, Heidel JD, Bartlett DW, Davis ME, Triche TJ. Hu-Lieskovan S, et al. Among authors: heidel jd. Cancer Res. 2005 Oct 1;65(19):8984-92. doi: 10.1158/0008-5472.CAN-05-0565. Cancer Res. 2005. PMID: 16204072

4

Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo.

Heidel JD, Liu JY, Yen Y, Zhou B, Heale BS, Rossi JJ, Bartlett DW, Davis ME. Heidel JD, et al. Clin Cancer Res. 2007 Apr 1;13(7):2207-15. doi: 10.1158/1078-0432.CCR-06-2218. Clin Cancer Res. 2007. PMID: 17404105

5

Cyclodextrin-containing polycations for nucleic acid delivery.

Heidel JD. Heidel JD. Cold Spring Harb Protoc. 2011 Nov 1;2011(11):1319-22. doi: 10.1101/pdb.top066639. Cold Spring Harb Protoc. 2011. PMID: 22046045

6

Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.

Heidel JD, Yu Z, Liu JY, Rele SM, Liang Y, Zeidan RK, Kornbrust DJ, Davis ME. Heidel JD, et al. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5715-21. doi: 10.1073/pnas.0701458104. Epub 2007 Mar 22. Proc Natl Acad Sci U S A. 2007. PMID: 17379663 Free PMC article.

7

Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models.

Schluep T, Hwang J, Cheng J, Heidel JD, Bartlett DW, Hollister B, Davis ME. Schluep T, et al. Among authors: heidel jd. Clin Cancer Res. 2006 Mar 1;12(5):1606-14. doi: 10.1158/1078-0432.CCR-05-1566. Clin Cancer Res. 2006. PMID: 16533788

8

Clinical developments in nanotechnology for cancer therapy.

Heidel JD, Davis ME. Heidel JD, et al. Pharm Res. 2011 Feb;28(2):187-99. doi: 10.1007/s11095-010-0178-7. Epub 2010 Jun 12. Pharm Res. 2011. PMID: 20549313 Review.

9

Lack of interferon response in animals to naked siRNAs.

Heidel JD, Hu S, Liu XF, Triche TJ, Davis ME. Heidel JD, et al. Nat Biotechnol. 2004 Dec;22(12):1579-82. doi: 10.1038/nbt1038. Epub 2004 Nov 21. Nat Biotechnol. 2004. PMID: 15558046

10

Imidazole groups on a linear, cyclodextrin-containing polycation produce enhanced gene delivery via multiple processes.

Mishra S, Heidel JD, Webster P, Davis ME. Mishra S, et al. Among authors: heidel jd. J Control Release. 2006 Nov 28;116(2):179-91. doi: 10.1016/j.jconrel.2006.06.018. Epub 2006 Jun 27. J Control Release. 2006. PMID: 16891028

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