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Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.
Wang YE, Li B, Carlson JM, Streeck H, Gladden AD, Goodman R, Schneidewind A, Power KA, Toth I, Frahm N, Alter G, Brander C, Carrington M, Walker BD, Altfeld M, Heckerman D, Allen TM. Wang YE, et al. Among authors: heckerman d. J Virol. 2009 Feb;83(4):1845-55. doi: 10.1128/JVI.01061-08. Epub 2008 Nov 26. J Virol. 2009. PMID: 19036810 Free PMC article.
HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.
Rousseau CM, Daniels MG, Carlson JM, Kadie C, Crawford H, Prendergast A, Matthews P, Payne R, Rolland M, Raugi DN, Maust BS, Learn GH, Nickle DC, Coovadia H, Ndung'u T, Frahm N, Brander C, Walker BD, Goulder PJ, Bhattacharya T, Heckerman DE, Korber BT, Mullins JI. Rousseau CM, et al. Among authors: heckerman de. J Virol. 2008 Jul;82(13):6434-46. doi: 10.1128/JVI.02455-07. Epub 2008 Apr 23. J Virol. 2008. PMID: 18434400 Free PMC article.
Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1.
Brumme ZL, Brumme CJ, Heckerman D, Korber BT, Daniels M, Carlson J, Kadie C, Bhattacharya T, Chui C, Szinger J, Mo T, Hogg RS, Montaner JS, Frahm N, Brander C, Walker BD, Harrigan PR. Brumme ZL, et al. Among authors: heckerman d. PLoS Pathog. 2007 Jul;3(7):e94. doi: 10.1371/journal.ppat.0030094. PLoS Pathog. 2007. PMID: 17616974 Free PMC article.
Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes.
Miura T, Brockman MA, Brumme CJ, Brumme ZL, Carlson JM, Pereyra F, Trocha A, Addo MM, Block BL, Rothchild AC, Baker BM, Flynn T, Schneidewind A, Li B, Wang YE, Heckerman D, Allen TM, Walker BD. Miura T, et al. Among authors: heckerman d. J Virol. 2008 Sep;82(17):8422-30. doi: 10.1128/JVI.00535-08. Epub 2008 Jun 18. J Virol. 2008. PMID: 18562530 Free PMC article.
Central role of reverting mutations in HLA associations with human immunodeficiency virus set point.
Matthews PC, Prendergast A, Leslie A, Crawford H, Payne R, Rousseau C, Rolland M, Honeyborne I, Carlson J, Kadie C, Brander C, Bishop K, Mlotshwa N, Mullins JI, Coovadia H, Ndung'u T, Walker BD, Heckerman D, Goulder PJ. Matthews PC, et al. Among authors: heckerman d. J Virol. 2008 Sep;82(17):8548-59. doi: 10.1128/JVI.00580-08. Epub 2008 Jul 2. J Virol. 2008. PMID: 18596105 Free PMC article.
Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection.
Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, Eichbaum Q, Block BL, Baker B, Kadie C, Markowitz M, Jessen H, Kelleher AD, Rosenberg E, Kaldor J, Yuki Y, Carrington M, Allen TM, Mallal S, Altfeld M, Heckerman D, Walker BD. Brumme ZL, et al. Among authors: heckerman d. J Virol. 2008 Sep;82(18):9216-27. doi: 10.1128/JVI.01041-08. Epub 2008 Jul 9. J Virol. 2008. PMID: 18614631 Free PMC article.
HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering.
Matthews PC, Leslie AJ, Katzourakis A, Crawford H, Payne R, Prendergast A, Power K, Kelleher AD, Klenerman P, Carlson J, Heckerman D, Ndung'u T, Walker BD, Allen TM, Pybus OG, Goulder PJ. Matthews PC, et al. Among authors: heckerman d. J Virol. 2009 May;83(9):4605-15. doi: 10.1128/JVI.02017-08. Epub 2009 Feb 25. J Virol. 2009. PMID: 19244334 Free PMC article.
126 results