Imbert T - Search Results

1

F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.

Barret JM, Kruczynski A, Vispé S, Annereau JP, Brel V, Guminski Y, Delcros JG, Lansiaux A, Guilbaud N, Imbert T, Bailly C. Barret JM, et al. Among authors: imbert t. Cancer Res. 2008 Dec 1;68(23):9845-53. doi: 10.1158/0008-5472.CAN-08-2748. Cancer Res. 2008. PMID: 19047165

2

Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase.

Kruczynski A, Mayer P, Marchand A, Vispé S, Fournier E, Annereau JP, Brel V, Barret JM, Delsol G, Imbert T, Fahy J, Bailly C. Kruczynski A, et al. Among authors: imbert t. Anticancer Drugs. 2009 Jun;20(5):364-72. doi: 10.1097/CAD.0b013e32832a2ed9. Anticancer Drugs. 2009. PMID: 19322071

3

Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system.

Guminski Y, Grousseaud M, Cugnasse S, Brel V, Annereau JP, Vispé S, Guilbaud N, Barret JM, Bailly C, Imbert T. Guminski Y, et al. Among authors: imbert t. Bioorg Med Chem Lett. 2009 May 1;19(9):2474-7. doi: 10.1016/j.bmcl.2009.03.052. Epub 2009 Mar 18. Bioorg Med Chem Lett. 2009. PMID: 19332372

4

Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system.

Kruczynski A, Vandenberghe I, Pillon A, Pesnel S, Goetsch L, Barret JM, Guminski Y, Le Pape A, Imbert T, Bailly C, Guilbaud N. Kruczynski A, et al. Among authors: imbert t. Invest New Drugs. 2011 Feb;29(1):9-21. doi: 10.1007/s10637-009-9328-3. Epub 2009 Sep 24. Invest New Drugs. 2011. PMID: 19777159

5

A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment.

Annereau JP, Brel V, Dumontet C, Guminski Y, Imbert T, Broussas M, Vispé S, Bréand S, Guilbaud N, Barret JM, Bailly C. Annereau JP, et al. Among authors: imbert t. Leuk Res. 2010 Oct;34(10):1383-9. doi: 10.1016/j.leukres.2009.12.021. Epub 2010 Jan 22. Leuk Res. 2010. PMID: 20096930

6

99mTc-HYNIC-spermine for imaging polyamine transport system-positive tumours: preclinical evaluation.

Pesnel S, Guminski Y, Pillon A, Lerondel S, Imbert T, Guilbaud N, Kruczynski A, Bailly C, Le Pape A. Pesnel S, et al. Among authors: imbert t. Eur J Nucl Med Mol Imaging. 2011 Oct;38(10):1832-41. doi: 10.1007/s00259-011-1857-2. Epub 2011 Jun 10. Eur J Nucl Med Mol Imaging. 2011. PMID: 21660624

7

Requirements for P-glycoprotein recognition based on structure-activity relationships in the podophyllotoxin series.

Etievant C, Schambel P, Guminski Y, Barret JM, Imbert T, Hill BT. Etievant C, et al. Among authors: imbert t. Anticancer Drug Des. 1998 Jun;13(4):317-36. Anticancer Drug Des. 1998. PMID: 9627671

8

Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases.

Kruczynski A, Etiévant C, Perrin D, Imbert T, Colpaert F, Hill BT. Kruczynski A, et al. Among authors: imbert t. Br J Cancer. 2000 Dec;83(11):1516-24. doi: 10.1054/bjoc.2000.1428. Br J Cancer. 2000. PMID: 11076662 Free PMC article.

9

F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action.

Perrin D, van Hille B, Barret JM, Kruczynski A, Etiévant C, Imbert T, Hill BT. Perrin D, et al. Among authors: imbert t. Biochem Pharmacol. 2000 Apr 1;59(7):807-19. doi: 10.1016/s0006-2952(99)00382-2. Biochem Pharmacol. 2000. PMID: 10718339

10

Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.

Daley L, Guminski Y, Demerseman P, Kruczynski A, Etiévant C, Imbert T, Hill BT, Monneret C. Daley L, et al. Among authors: imbert t. J Med Chem. 1998 Nov 5;41(23):4475-85. doi: 10.1021/jm9800752. J Med Chem. 1998. PMID: 9804687

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