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Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control.
Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, Rood JE, Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G, Kwan R, McLaughlin M, Stallings S, Rehm C, O'Shea MA, Mican J, Packard BZ, Komoriya A, Palmer S, Wiegand AP, Maldarelli F, Coffin JM, Mellors JW, Hallahan CW, Follman DA, Connors M. Migueles SA, et al. Among authors: compton aa. Immunity. 2008 Dec 19;29(6):1009-21. doi: 10.1016/j.immuni.2008.10.010. Epub 2008 Dec 8. Immunity. 2008. PMID: 19062316 Free PMC article.
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2.
Shi G, Chiramel AI, Li T, Lai KK, Kenney AD, Zani A, Eddy A, Majdoul S, Zhang L, Dempsey T, Beare PA, Kar S, Yewdell JW, Best SM, Yount JS, Compton AA. Shi G, et al. Among authors: compton aa. bioRxiv [Preprint]. 2022 Aug 30:2021.04.15.440067. doi: 10.1101/2021.04.15.440067. bioRxiv. 2022. Update in: J Clin Invest. 2022 Dec 15;132(24):e160766. doi: 10.1172/JCI160766 PMID: 33880473 Free PMC article. Updated. Preprint.
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2.
Shi G, Chiramel AI, Li T, Lai KK, Kenney AD, Zani A, Eddy AC, Majdoul S, Zhang L, Dempsey T, Beare PA, Kar S, Yewdell JW, Best SM, Yount JS, Compton AA. Shi G, et al. Among authors: compton aa. J Clin Invest. 2022 Dec 15;132(24):e160766. doi: 10.1172/JCI160766. J Clin Invest. 2022. PMID: 36264642 Free PMC article.
IFITM3 requires an amphipathic helix for antiviral activity.
Chesarino NM, Compton AA, McMichael TM, Kenney AD, Zhang L, Soewarna V, Davis M, Schwartz O, Yount JS. Chesarino NM, et al. Among authors: compton aa. EMBO Rep. 2017 Oct;18(10):1740-1751. doi: 10.15252/embr.201744100. Epub 2017 Aug 23. EMBO Rep. 2017. PMID: 28835547 Free PMC article.
49 results