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Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease.
Zheng W, Padia J, Urban DJ, Jadhav A, Goker-Alpan O, Simeonov A, Goldin E, Auld D, LaMarca ME, Inglese J, Austin CP, Sidransky E. Zheng W, et al. Among authors: lamarca me. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13192-7. doi: 10.1073/pnas.0705637104. Epub 2007 Aug 1. Proc Natl Acad Sci U S A. 2007. PMID: 17670938 Free PMC article.
Glucocerebrosidase mutations in subjects with parkinsonism.
Lwin A, Orvisky E, Goker-Alpan O, LaMarca ME, Sidransky E. Lwin A, et al. Among authors: lamarca me. Mol Genet Metab. 2004 Jan;81(1):70-3. doi: 10.1016/j.ymgme.2003.11.004. Mol Genet Metab. 2004. PMID: 14728994
Parkinsonism among Gaucher disease carriers.
Goker-Alpan O, Schiffmann R, LaMarca ME, Nussbaum RL, McInerney-Leo A, Sidransky E. Goker-Alpan O, et al. Among authors: lamarca me. J Med Genet. 2004 Dec;41(12):937-40. doi: 10.1136/jmg.2004.024455. J Med Genet. 2004. PMID: 15591280 Free PMC article.
In silico and functional studies of the regulation of the glucocerebrosidase gene.
Blech-Hermoni YN, Ziegler SG, Hruska KS, Stubblefield BK, Lamarca ME, Portnoy ME; NISC Comparative Sequencing Program; Green ED, Sidransky E. Blech-Hermoni YN, et al. Among authors: lamarca me. Mol Genet Metab. 2010 Mar;99(3):275-82. doi: 10.1016/j.ymgme.2009.10.189. Epub 2009 Nov 4. Mol Genet Metab. 2010. PMID: 20004604 Free PMC article.
36 results