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Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data.
Price WN 2nd, Chen Y, Handelman SK, Neely H, Manor P, Karlin R, Nair R, Liu J, Baran M, Everett J, Tong SN, Forouhar F, Swaminathan SS, Acton T, Xiao R, Luft JR, Lauricella A, DeTitta GT, Rost B, Montelione GT, Hunt JF. Price WN 2nd, et al. Among authors: forouhar f. Nat Biotechnol. 2009 Jan;27(1):51-7. doi: 10.1038/nbt.1514. Nat Biotechnol. 2009. PMID: 19079241 Free PMC article.
Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.
Forouhar F, Hussain M, Farid R, Benach J, Abashidze M, Edstrom WC, Vorobiev SM, Xiao R, Acton TB, Fu Z, Kim JJ, Miziorko HM, Montelione GT, Hunt JF. Forouhar F, et al. J Biol Chem. 2006 Mar 17;281(11):7533-45. doi: 10.1074/jbc.M507996200. Epub 2005 Dec 5. J Biol Chem. 2006. PMID: 16330546 Free article.
Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase.
Forouhar F, Anderson JL, Mowat CG, Vorobiev SM, Hussain A, Abashidze M, Bruckmann C, Thackray SJ, Seetharaman J, Tucker T, Xiao R, Ma LC, Zhao L, Acton TB, Montelione GT, Chapman SK, Tong L. Forouhar F, et al. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):473-8. doi: 10.1073/pnas.0610007104. Epub 2006 Dec 29. Proc Natl Acad Sci U S A. 2007. PMID: 17197414 Free PMC article.
Functional insights from structural genomics.
Forouhar F, Kuzin A, Seetharaman J, Lee I, Zhou W, Abashidze M, Chen Y, Yong W, Janjua H, Fang Y, Wang D, Cunningham K, Xiao R, Acton TB, Pichersky E, Klessig DF, Porter CW, Montelione GT, Tong L. Forouhar F, et al. J Struct Funct Genomics. 2007 Sep;8(2-3):37-44. doi: 10.1007/s10969-007-9018-3. Epub 2007 Jun 23. J Struct Funct Genomics. 2007. PMID: 17588214
The structural basis of cyclic diguanylate signal transduction by PilZ domains.
Benach J, Swaminathan SS, Tamayo R, Handelman SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, Seetharaman J, Camilli A, Hunt JF. Benach J, et al. Among authors: forouhar f. EMBO J. 2007 Dec 12;26(24):5153-66. doi: 10.1038/sj.emboj.7601918. Epub 2007 Nov 22. EMBO J. 2007. PMID: 18034161 Free PMC article.
156 results