Marzec M - Search Results

1

Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).

Marzec M, Zhang Q, Goradia A, Raghunath PN, Liu X, Paessler M, Wang HY, Wysocka M, Cheng M, Ruggeri BA, Wasik MA. Marzec M, et al. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20852-7. doi: 10.1073/pnas.0810958105. Epub 2008 Dec 16. Proc Natl Acad Sci U S A. 2008. PMID: 19088198 Free PMC article.

2

Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.

Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA. Marzec M, et al. Oncogene. 2007 Feb 8;26(6):813-21. doi: 10.1038/sj.onc.1209843. Epub 2006 Aug 7. Oncogene. 2007. PMID: 16909118

3

Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA. Marzec M, et al. Oncogene. 2007 Aug 16;26(38):5606-14. doi: 10.1038/sj.onc.1210346. Epub 2007 Mar 12. Oncogene. 2007. PMID: 17353907

4

Oncogenic kinase NPM/ALK induces expression of HIF1α mRNA.

Marzec M, Liu X, Wong W, Yang Y, Pasha T, Kantekure K, Zhang P, Woetmann A, Cheng M, Odum N, Wasik MA. Marzec M, et al. Oncogene. 2011 Mar 17;30(11):1372-8. doi: 10.1038/onc.2010.505. Epub 2010 Nov 22. Oncogene. 2011. PMID: 21102525

5

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

Zhang Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA. Zhang Q, et al. Among authors: marzec m. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6948-53. doi: 10.1073/pnas.0501959102. Epub 2005 May 3. Proc Natl Acad Sci U S A. 2005. PMID: 15870198 Free PMC article.

6

Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3.

Marzec M, Kasprzycka M, Ptasznik A, Wlodarski P, Zhang Q, Odum N, Wasik MA. Marzec M, et al. Lab Invest. 2005 Dec;85(12):1544-54. doi: 10.1038/labinvest.3700348. Lab Invest. 2005. PMID: 16170336 Free article.

7

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

Kasprzycka M, Majewski M, Wang ZJ, Ptasznik A, Wysocka M, Zhang Q, Marzec M, Gimotty P, Crompton MR, Wasik MA. Kasprzycka M, et al. Among authors: marzec m. Am J Pathol. 2006 May;168(5):1631-41. doi: 10.2353/ajpath.2006.050521. Am J Pathol. 2006. PMID: 16651629 Free PMC article.

8

Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3.

Kasprzycka M, Marzec M, Liu X, Zhang Q, Wasik MA. Kasprzycka M, et al. Among authors: marzec m. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9964-9. doi: 10.1073/pnas.0603507103. Epub 2006 Jun 9. Proc Natl Acad Sci U S A. 2006. PMID: 16766651 Free PMC article.

9

Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches.

Wasik MA, Zhang Q, Marzec M, Kasprzycka M, Wang HY, Liu X. Wasik MA, et al. Among authors: marzec m. Semin Oncol. 2009 Apr;36(2 Suppl 1):S27-35. doi: 10.1053/j.seminoncol.2009.02.007. Semin Oncol. 2009. PMID: 19393833

10

Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming.

Marzec M, Halasa K, Liu X, Wang HY, Cheng M, Baldwin D, Tobias JW, Schuster SJ, Woetmann A, Zhang Q, Turner SD, Ødum N, Wasik MA. Marzec M, et al. J Immunol. 2013 Dec 15;191(12):6200-7. doi: 10.4049/jimmunol.1300744. Epub 2013 Nov 11. J Immunol. 2013. PMID: 24218456 Free PMC article.

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