Jarman M - Search Results

1

Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs).

Gorsuch S, Bavetsias V, Rowlands MG, Aherne GW, Workman P, Jarman M, McDonald E. Gorsuch S, et al. Among authors: jarman m. Bioorg Med Chem. 2009 Jan 15;17(2):467-74. doi: 10.1016/j.bmc.2008.11.079. Epub 2008 Dec 7. Bioorg Med Chem. 2009. PMID: 19101154

2

Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity.

Stimson L, Rowlands MG, Newbatt YM, Smith NF, Raynaud FI, Rogers P, Bavetsias V, Gorsuch S, Jarman M, Bannister A, Kouzarides T, McDonald E, Workman P, Aherne GW. Stimson L, et al. Among authors: jarman m. Mol Cancer Ther. 2005 Oct;4(10):1521-32. doi: 10.1158/1535-7163.MCT-05-0135. Mol Cancer Ther. 2005. PMID: 16227401

3

Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors.

Wilson SC, Atrash B, Barlow C, Eccles S, Fischer PM, Hayes A, Kelland L, Jackson W, Jarman M, Mirza A, Moreno J, Nutley BP, Raynaud FI, Sheldrake P, Walton M, Westwood R, Whittaker S, Workman P, McDonald E. Wilson SC, et al. Among authors: jarman m. Bioorg Med Chem. 2011 Nov 15;19(22):6949-65. doi: 10.1016/j.bmc.2011.08.051. Epub 2011 Aug 31. Bioorg Med Chem. 2011. PMID: 21982796

4

Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer.

Potter GA, Barrie SE, Jarman M, Rowlands MG. Potter GA, et al. Among authors: jarman m. J Med Chem. 1995 Jun 23;38(13):2463-71. doi: 10.1021/jm00013a022. J Med Chem. 1995. PMID: 7608911

5

Homologs of idoxifene: variation of estrogen receptor binding and calmodulin antagonism with chain length.

Hardcastle IR, Rowlands MG, Grimshaw RM, Houghton J, Jarman M. Hardcastle IR, et al. Among authors: jarman m. J Med Chem. 1996 Feb 16;39(4):999-1004. doi: 10.1021/jm9505472. J Med Chem. 1996. PMID: 8632423

6

Solid-phase synthesis of novel inhibitors of farnesyl transferase.

Barber AM, Hardcastle IR, Rowlands MG, Nutley BP, Marriott JH, Jarman M. Barber AM, et al. Among authors: jarman m. Bioorg Med Chem Lett. 1999 Feb 22;9(4):623-6. doi: 10.1016/s0960-894x(99)00043-8. Bioorg Med Chem Lett. 1999. PMID: 10098677

7

Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis.

Jarman M, Barrie SE, Deadman JJ, Houghton J, McCague R, Rowlands MG. Jarman M, et al. J Med Chem. 1990 Sep;33(9):2452-5. doi: 10.1021/jm00171a019. J Med Chem. 1990. PMID: 2391687

8

Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analogue, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives.

Laughton CA, McKenna R, Neidle S, Jarman M, McCague R, Rowlands MG. Laughton CA, et al. Among authors: jarman m. J Med Chem. 1990 Sep;33(9):2673-9. doi: 10.1021/jm00171a052. J Med Chem. 1990. PMID: 2391706

9

Selective inhibition of cholesterol side-chain cleavage by potential pro-drug forms of aminoglutethimide.

Jarman M, Barrie SE, Leung CS, Rowlands MG. Jarman M, et al. Anticancer Drug Des. 1988 Dec;3(3):185-90. Anticancer Drug Des. 1988. PMID: 3264700

10

Analogues of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity.

Rowlands MG, Bunnett MA, Foster AB, Jarman M, Stanek J, Schweizer E. Rowlands MG, et al. Among authors: jarman m. J Med Chem. 1988 May;31(5):971-6. doi: 10.1021/jm00400a014. J Med Chem. 1988. PMID: 3361583

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