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Page 1
The efficacy and safety of cilomilast in COPD.
Rennard S, Knobil K, Rabe KF, Morris A, Schachter N, Locantore N, Canonica WG, Zhu Y, Barnhart F. Rennard S, et al. Among authors: rabe kf. Drugs. 2008;68 Suppl 2:3-57. doi: 10.2165/0003495-200868002-00002. Drugs. 2008. PMID: 19105585 Review.
Antiinflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease.
Gamble E, Grootendorst DC, Brightling CE, Troy S, Qiu Y, Zhu J, Parker D, Matin D, Majumdar S, Vignola AM, Kroegel C, Morell F, Hansel TT, Rennard SI, Compton C, Amit O, Tat T, Edelson J, Pavord ID, Rabe KF, Barnes NC, Jeffery PK. Gamble E, et al. Among authors: rabe kf. Am J Respir Crit Care Med. 2003 Oct 15;168(8):976-82. doi: 10.1164/rccm.200212-1490OC. Epub 2003 Jun 19. Am J Respir Crit Care Med. 2003. PMID: 12816740 Clinical Trial.
Chronic obstructive pulmonary disease phenotypes: the future of COPD.
Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, Macnee W, Make BJ, Rabe KF, Rennard SI, Sciurba FC, Silverman EK, Vestbo J, Washko GR, Wouters EF, Martinez FJ. Han MK, et al. Among authors: rabe kf. Am J Respir Crit Care Med. 2010 Sep 1;182(5):598-604. doi: 10.1164/rccm.200912-1843CC. Epub 2010 Jun 3. Am J Respir Crit Care Med. 2010. PMID: 20522794 Free PMC article.
Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4.
Michalski J, Kanaji N, Liu X, Nogel S, Wang X, Basma H, Nakanishi M, Sato T, Gunji Y, Fahrid M, Nelson A, Muller KC, Holz O, Magnussen H, Rabe KF, Toews ML, Rennard SI. Michalski J, et al. Among authors: rabe kf. Am J Respir Cell Mol Biol. 2012 Dec;47(6):729-37. doi: 10.1165/rcmb.2012-0057OC. Epub 2012 Oct 4. Am J Respir Cell Mol Biol. 2012. PMID: 23043089 Free PMC article.
Anti-inflammatory effects of budesonide in human lung fibroblast are independent of histone deacetylase 2.
Wang X, Nelson A, Weiler ZM, Patil A, Sato T, Kanaji N, Nakanishi M, Michalski J, Farid M, Basma H, Levan TD, Miller-Larsson A, Wieslander E, Muller KC, Holz O, Magnussen H, Rabe KF, Liu X, Rennard SI. Wang X, et al. Among authors: rabe kf. J Inflamm Res. 2013 Aug 20;6:109-19. doi: 10.2147/JIR.S43736. eCollection 2013. J Inflamm Res. 2013. PMID: 24062615 Free PMC article.
Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells.
Basma H, Gunji Y, Iwasawa S, Nelson A, Farid M, Ikari J, Liu X, Wang X, Michalski J, Smith L, Iqbal J, El Behery R, West W, Yelamanchili S, Rennard D, Holz O, Mueller KC, Magnussen H, Rabe K, Castaldi PJ, Rennard SI. Basma H, et al. Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15;306(6):L552-65. doi: 10.1152/ajplung.00255.2013. Epub 2014 Jan 31. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24487392 Free PMC article.
Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE(2)SPOND rationale and study design.
Rennard SI, Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Siddiqui S, Anzueto A, Zhu H. Rennard SI, et al. Among authors: rabe kf. Int J Chron Obstruct Pulmon Dis. 2016 Aug 17;11:1921-8. doi: 10.2147/COPD.S109661. eCollection 2016. Int J Chron Obstruct Pulmon Dis. 2016. PMID: 27574416 Free PMC article. Clinical Trial.
Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial.
Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Anzueto A, Alagappan VK, Siddiqui S, Rekeda L, Miller CJ, Zetterstrand S, Reisner C, Rennard SI. Martinez FJ, et al. Among authors: rabe kf. Am J Respir Crit Care Med. 2016 Sep 1;194(5):559-67. doi: 10.1164/rccm.201607-1349OC. Am J Respir Crit Care Med. 2016. PMID: 27585384 Clinical Trial.
Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Patients With COPD.
Martinez FJ, Rabe KF, Ferguson GT, Fabbri LM, Rennard S, Feldman GJ, Sethi S, Spangenthal S, Gottschlich GM, Rodriguez-Roisin R, Arora S, Siler TM, Siddiqui S, Darken P, Fischer T, Maes A, Golden M, Orevillo C, Reisner C. Martinez FJ, et al. Among authors: rabe kf. Chest. 2017 Feb;151(2):340-357. doi: 10.1016/j.chest.2016.11.028. Epub 2016 Dec 1. Chest. 2017. PMID: 27916620 Free article. Clinical Trial.
577 results