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Secretion of the Notch-1 Abeta-like peptide during Notch signaling.
Okochi M, Fukumori A, Jiang J, Itoh N, Kimura R, Steiner H, Haass C, Tagami S, Takeda M. Okochi M, et al. Among authors: kimura r. J Biol Chem. 2006 Mar 24;281(12):7890-8. doi: 10.1074/jbc.M513250200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16434391 Free article.
Altered localization of amyloid precursor protein under endoplasmic reticulum stress.
Kudo T, Okumura M, Imaizumi K, Araki W, Morihara T, Tanimukai H, Kamagata E, Tabuchi N, Kimura R, Kanayama D, Fukumori A, Tagami S, Okochi M, Kubo M, Tanii H, Tohyama M, Tabira T, Takeda M. Kudo T, et al. Among authors: kimura r. Biochem Biophys Res Commun. 2006 Jun 2;344(2):525-30. doi: 10.1016/j.bbrc.2006.03.173. Epub 2006 Apr 5. Biochem Biophys Res Commun. 2006. PMID: 16630560
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
Kimura R, Kamino K, Yamamoto M, Nuripa A, Kida T, Kazui H, Hashimoto R, Tanaka T, Kudo T, Yamagata H, Tabara Y, Miki T, Akatsu H, Kosaka K, Funakoshi E, Nishitomi K, Sakaguchi G, Kato A, Hattori H, Uema T, Takeda M. Kimura R, et al. Hum Mol Genet. 2007 Jan 1;16(1):15-23. doi: 10.1093/hmg/ddl437. Epub 2006 Nov 29. Hum Mol Genet. 2007. PMID: 17135279
A molecular chaperone inducer protects neurons from ER stress.
Kudo T, Kanemoto S, Hara H, Morimoto N, Morihara T, Kimura R, Tabira T, Imaizumi K, Takeda M. Kudo T, et al. Among authors: kimura r. Cell Death Differ. 2008 Feb;15(2):364-75. doi: 10.1038/sj.cdd.4402276. Epub 2007 Nov 30. Cell Death Differ. 2008. PMID: 18049481
KIBRA genetic polymorphism influences episodic memory in Alzheimer's disease, but does not show association with disease in a Japanese cohort.
Hayashi N, Kazui H, Kamino K, Tokunaga H, Takaya M, Yokokoji M, Kimura R, Kito Y, Wada T, Nomura K, Sugiyama H, Yamamoto D, Yoshida T, Currais A, Soriano S, Hamasaki T, Yamamoto M, Yasuda Y, Hashimoto R, Tanimukai H, Tagami S, Okochi M, Tanaka T, Kudo T, Morihara T, Takeda M. Hayashi N, et al. Among authors: kimura r. Dement Geriatr Cogn Disord. 2010;30(4):302-8. doi: 10.1159/000320482. Epub 2010 Sep 25. Dement Geriatr Cogn Disord. 2010. PMID: 20881395
Meta-analysis of the association between variants in SORL1 and Alzheimer disease.
Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, Riemenschneider M, Owen M, Harold D, Hollingworth P, Cellini E, Sorbi S, Nacmias B, Takeda M, Pericak-Vance MA, Haines JL, Younkin S, Williams J, van Broeckhoven C, Farrer LA, St George-Hyslop PH, Mayeux R; Genetic and Environmental Risk in Alzheimer Disease 1 Consortium. Reitz C, et al. Among authors: kimura r. Arch Neurol. 2011 Jan;68(1):99-106. doi: 10.1001/archneurol.2010.346. Arch Neurol. 2011. PMID: 21220680 Free PMC article.
1,156 results