Kim KW - Search Results

1

A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy.

Kim WY, Chang DJ, Hennessy B, Kang HJ, Yoo J, Han SH, Kim YS, Park HJ, Seo SY, Mills G, Kim KW, Hong WK, Suh YG, Lee HY. Kim WY, et al. Among authors: kim ys, kim kw. Cancer Prev Res (Phila). 2008 Dec;1(7):577-87. doi: 10.1158/1940-6207.CAPR-08-0184. Cancer Prev Res (Phila). 2008. PMID: 19139008 Free PMC article.

2

Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.

Oh SH, Woo JK, Jin Q, Kang HJ, Jeong JW, Kim KW, Hong WK, Lee HY. Oh SH, et al. Among authors: kim kw. Int J Cancer. 2008 Jan 1;122(1):5-14. doi: 10.1002/ijc.23075. Int J Cancer. 2008. PMID: 17764071

3

Structural basis for depletion of heat shock protein 90 client proteins by deguelin.

Oh SH, Woo JK, Yazici YD, Myers JN, Kim WY, Jin Q, Hong SS, Park HJ, Suh YG, Kim KW, Hong WK, Lee HY. Oh SH, et al. Among authors: kim wy, kim kw. J Natl Cancer Inst. 2007 Jun 20;99(12):949-61. doi: 10.1093/jnci/djm007. Epub 2007 Jun 12. J Natl Cancer Inst. 2007. PMID: 17565155

4

A novel antitumor activity of deguelin targeting the insulin-like growth factor (IGF) receptor pathway via up-regulation of IGF-binding protein-3 expression in breast cancer.

Suh YA, Kim JH, Sung MA, Boo HJ, Yun HJ, Lee SH, Lee HJ, Min HY, Suh YG, Kim KW, Lee HY. Suh YA, et al. Among authors: kim kw, kim jh. Cancer Lett. 2013 May 10;332(1):102-9. doi: 10.1016/j.canlet.2013.01.022. Epub 2013 Jan 21. Cancer Lett. 2013. PMID: 23348700 Free PMC article.

5

Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.

Lee SC, Min HY, Choi H, Kim HS, Kim KC, Park SJ, Seong MA, Seo JH, Park HJ, Suh YG, Kim KW, Hong HS, Kim H, Lee MY, Lee J, Lee HY. Lee SC, et al. Among authors: kim h, kim kc, kim hs, kim kw. Mol Pharmacol. 2015 Aug;88(2):245-55. doi: 10.1124/mol.114.096883. Epub 2015 May 14. Mol Pharmacol. 2015. PMID: 25976766

6

Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors.

Kim HS, Hong M, Lee SC, Lee HY, Suh YG, Oh DC, Seo JH, Choi H, Kim JY, Kim KW, Kim JH, Kim J, Kim YM, Park SJ, Park HJ, Lee J. Kim HS, et al. Among authors: kim jy, kim ym, kim j, kim kw, kim jh. Eur J Med Chem. 2015 Nov 2;104:157-64. doi: 10.1016/j.ejmech.2015.09.033. Epub 2015 Sep 30. Eur J Med Chem. 2015. PMID: 26457742

7

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity.

Lee SC, Min HY, Choi H, Bae SY, Park KH, Hyun SY, Lee HJ, Moon J, Park SH, Kim JY, An H, Park SJ, Seo JH, Lee S, Kim YM, Park HJ, Lee SK, Lee J, Lee J, Kim KW, Suh YG, Lee HY. Lee SC, et al. Among authors: kim jy, kim ym, kim kw. Cancer Res. 2016 Feb 1;76(3):686-99. doi: 10.1158/0008-5472.CAN-15-1492. Epub 2015 Dec 8. Cancer Res. 2016. PMID: 26645561

8

Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors.

Kim HS, Hong M, Ann J, Yoon S, Nguyen CT, Lee SC, Lee HY, Suh YG, Seo JH, Choi H, Kim JY, Kim KW, Kim J, Kim YM, Park SJ, Park HJ, Lee J. Kim HS, et al. Among authors: kim jy, kim ym, kim j, kim kw. Bioorg Med Chem. 2016 Nov 15;24(22):6082-6093. doi: 10.1016/j.bmc.2016.09.067. Epub 2016 Sep 30. Bioorg Med Chem. 2016. PMID: 27745993

9

Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.

Kim HS, Hoang VH, Hong M, Chul Kim K, Ann J, Nguyen CT, Seo JH, Choi H, Yong Kim J, Kim KW, Sub Byun W, Lee S, Lee S, Suh YG, Chen J, Park HJ, Cho TM, Kim JY, Seo JH, Lee J. Kim HS, et al. Among authors: kim jy, kim kw. Bioorg Med Chem. 2019 Apr 1;27(7):1370-1381. doi: 10.1016/j.bmc.2019.02.040. Epub 2019 Feb 20. Bioorg Med Chem. 2019. PMID: 30827868

10

Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.

Chang DJ, An H, Kim KS, Kim HH, Jung J, Lee JM, Kim NJ, Han YT, Yun H, Lee S, Lee G, Lee S, Lee JS, Cha JH, Park JH, Park JW, Lee SC, Kim SG, Kim JH, Lee HY, Kim KW, Suh YG. Chang DJ, et al. Among authors: kim hh, kim sg, kim ks, kim nj, kim kw, kim jh. J Med Chem. 2012 Dec 27;55(24):10863-84. doi: 10.1021/jm301488q. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23186287

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