Smith E - Search Results

1

Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites.

Dalvie D, Obach RS, Kang P, Prakash C, Loi CM, Hurst S, Nedderman A, Goulet L, Smith E, Bu HZ, Smith DA. Dalvie D, et al. Among authors: smith e, smith da. Chem Res Toxicol. 2009 Feb;22(2):357-68. doi: 10.1021/tx8004357. Chem Res Toxicol. 2009. PMID: 19146377

2

Bioactivation of lumiracoxib by peroxidases and human liver microsomes: identification of multiple quinone imine intermediates and GSH adducts.

Kang P, Dalvie D, Smith E, Renner M. Kang P, et al. Among authors: smith e. Chem Res Toxicol. 2009 Jan;22(1):106-17. doi: 10.1021/tx8002356. Chem Res Toxicol. 2009. PMID: 19063590

3

NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.

Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS. Zhao SX, et al. Chem Res Toxicol. 2007 Nov;20(11):1649-57. doi: 10.1021/tx700132x. Epub 2007 Oct 2. Chem Res Toxicol. 2007. PMID: 17907785

4

Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes.

Kang P, Dalvie D, Smith E, Zhou S, Deese A. Kang P, et al. Among authors: smith e. Drug Metab Dispos. 2007 Jul;35(7):1081-8. doi: 10.1124/dmd.107.014860. Epub 2007 Apr 2. Drug Metab Dispos. 2007. PMID: 17403914

5

Bioactivation of flutamide metabolites by human liver microsomes.

Kang P, Dalvie D, Smith E, Zhou S, Deese A, Nieman JA. Kang P, et al. Among authors: smith e. Drug Metab Dispos. 2008 Jul;36(7):1425-37. doi: 10.1124/dmd.108.020370. Epub 2008 Apr 14. Drug Metab Dispos. 2008. PMID: 18411402

6

Biosynthesis of drug metabolites and quantitation using NMR spectroscopy for use in pharmacologic and drug metabolism studies.

Walker GS, Bauman JN, Ryder TF, Smith EB, Spracklin DK, Obach RS. Walker GS, et al. Drug Metab Dispos. 2014 Oct;42(10):1627-39. doi: 10.1124/dmd.114.059204. Epub 2014 Jul 22. Drug Metab Dispos. 2014. PMID: 25053618

7

In vitro metabolic activation of thiabendazole via 5-hydroxythiabendazole: identification of a glutathione conjugate of 5-hydroxythiabendazole.

Dalvie D, Smith E, Deese A, Bowlin S. Dalvie D, et al. Among authors: smith e. Drug Metab Dispos. 2006 Apr;34(4):709-17. doi: 10.1124/dmd.105.008094. Epub 2006 Jan 24. Drug Metab Dispos. 2006. PMID: 16434547

8

Metabolism, excretion and pharmacokinetics of [14C]crizotinib following oral administration to healthy subjects.

Johnson TR, Tan W, Goulet L, Smith EB, Yamazaki S, Walker GS, O'Gorman MT, Bedarida G, Zou HY, Christensen JG, Nguyen LN, Shen Z, Dalvie D, Bello A, Smith BJ. Johnson TR, et al. Xenobiotica. 2015 Jan;45(1):45-59. doi: 10.3109/00498254.2014.941964. Epub 2014 Jul 18. Xenobiotica. 2015. PMID: 25034009

9

Myeloperoxidase-mediated bioactivation of 5-hydroxythiabendazole: a possible mechanism of thiabendazole toxicity.

Jamieson JD, Smith EB, Dalvie DK, Stevens GJ, Yanochko GM. Jamieson JD, et al. Toxicol In Vitro. 2011 Aug;25(5):1061-6. doi: 10.1016/j.tiv.2011.04.007. Epub 2011 Apr 12. Toxicol In Vitro. 2011. PMID: 21513789

10

A phase I, open-label, mass balance study of [(14)C] dacomitinib (PF-00299804) in healthy male volunteers.

Bello CL, Smith E, Ruiz-Garcia A, Ni G, Alvey C, Loi CM. Bello CL, et al. Among authors: smith e. Cancer Chemother Pharmacol. 2013 Aug;72(2):379-85. doi: 10.1007/s00280-013-2207-9. Epub 2013 Jun 13. Cancer Chemother Pharmacol. 2013. PMID: 23760812 Clinical Trial.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

12,095 results

Search Page

Filters