McCurdy CE - Search Results

1

Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates.

McCurdy CE, Bishop JM, Williams SM, Grayson BE, Smith MS, Friedman JE, Grove KL. McCurdy CE, et al. J Clin Invest. 2009 Feb;119(2):323-35. doi: 10.1172/JCI32661. Epub 2009 Jan 19. J Clin Invest. 2009. PMID: 19147984 Free PMC article.

2

Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess.

Barbour LA, Mizanoor Rahman S, Gurevich I, Leitner JW, Fischer SJ, Roper MD, Knotts TA, Vo Y, McCurdy CE, Yakar S, Leroith D, Kahn CR, Cantley LC, Friedman JE, Draznin B. Barbour LA, et al. Among authors: mccurdy ce. J Biol Chem. 2005 Nov 11;280(45):37489-94. doi: 10.1074/jbc.M506967200. Epub 2005 Sep 8. J Biol Chem. 2005. PMID: 16166093 Free article.

3

Early foetal programming of hepatic gluconeogenesis: Glucocorticoids strike back.

McCurdy CE, Friedman JE. McCurdy CE, et al. Diabetologia. 2006 Jun;49(6):1138-41. doi: 10.1007/s00125-006-0256-x. Diabetologia. 2006. PMID: 16680490 No abstract available.

4

Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance.

del Rincon JP, Iida K, Gaylinn BD, McCurdy CE, Leitner JW, Barbour LA, Kopchick JJ, Friedman JE, Draznin B, Thorner MO. del Rincon JP, et al. Among authors: mccurdy ce. Diabetes. 2007 Jun;56(6):1638-46. doi: 10.2337/db06-0299. Epub 2007 Mar 15. Diabetes. 2007. PMID: 17363744

5

Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes.

Barbour LA, McCurdy CE, Hernandez TL, Kirwan JP, Catalano PM, Friedman JE. Barbour LA, et al. Among authors: mccurdy ce. Diabetes Care. 2007 Jul;30 Suppl 2:S112-9. doi: 10.2337/dc07-s202. Diabetes Care. 2007. PMID: 17596458 No abstract available.

6

Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues.

Wang H, Knaub LA, Jensen DR, Young Jung D, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la Houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Soo Choi C, Shulman GI, Kim JK, Friedman JE, Eckel RH. Wang H, et al. Among authors: mccurdy ce. Diabetes. 2009 Jan;58(1):116-24. doi: 10.2337/db07-1839. Epub 2008 Oct 24. Diabetes. 2009. PMID: 18952837 Free PMC article.

7

In vivo knockdown of p85alpha with an antisense oligonucleotide improves insulin sensitivity in Lep(ob/ob) and diet-induced obese mice.

Moriarty MW, McCurdy CE, Janssen RC, Shaw T, Leitner JW, Friedman JE, Draznin B. Moriarty MW, et al. Among authors: mccurdy ce. Horm Metab Res. 2009 Oct;41(10):757-61. doi: 10.1055/s-0029-1225363. Epub 2009 Jul 13. Horm Metab Res. 2009. PMID: 19598077

8

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation.

Kendrick AA, Choudhury M, Rahman SM, McCurdy CE, Friederich M, Van Hove JL, Watson PA, Birdsey N, Bao J, Gius D, Sack MN, Jing E, Kahn CR, Friedman JE, Jonscher KR. Kendrick AA, et al. Among authors: mccurdy ce. Biochem J. 2011 Feb 1;433(3):505-14. doi: 10.1042/BJ20100791. Biochem J. 2011. PMID: 21044047 Free PMC article.

9

Chronically increased S6K1 is associated with impaired IRS1 signaling in skeletal muscle of GDM women with impaired glucose tolerance postpartum.

Barbour LA, McCurdy CE, Hernandez TL, Friedman JE. Barbour LA, et al. Among authors: mccurdy ce. J Clin Endocrinol Metab. 2011 May;96(5):1431-41. doi: 10.1210/jc.2010-2116. Epub 2011 Feb 2. J Clin Endocrinol Metab. 2011. PMID: 21289241 Free PMC article.

10

Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice.

McCurdy CE, Schenk S, Holliday MJ, Philp A, Houck JA, Patsouris D, MacLean PS, Majka SM, Klemm DJ, Friedman JE. McCurdy CE, et al. Diabetes. 2012 Oct;61(10):2495-505. doi: 10.2337/db11-1433. Epub 2012 Jun 14. Diabetes. 2012. PMID: 22698915 Free PMC article.

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