Jin H - Search Results

1

Tricyclic HIV integrase inhibitors: VI. SAR studies of 'benzyl flipped' C3-substituted pyrroloquinolines.

Metobo S, Mish M, Jin H, Jabri S, Lansdown R, Chen X, Tsiang M, Wright M, Kim CU. Metobo S, et al. Among authors: jin h. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1187-90. doi: 10.1016/j.bmcl.2008.12.079. Epub 2008 Dec 25. Bioorg Med Chem Lett. 2009. PMID: 19167883

2

Effect of substitution on novel tricyclic HIV-1 integrase inhibitors.

Fardis M, Jin H, Jabri S, Cai RZ, Mish M, Tsiang M, Kim CU. Fardis M, et al. Among authors: jin h. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4031-5. doi: 10.1016/j.bmcl.2006.05.008. Epub 2006 May 23. Bioorg Med Chem Lett. 2006. PMID: 16716589

3

Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors.

Jin H, Cai RZ, Schacherer L, Jabri S, Tsiang M, Fardis M, Chen X, Chen JM, Kim CU. Jin H, et al. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3989-92. doi: 10.1016/j.bmcl.2006.05.016. Epub 2006 May 24. Bioorg Med Chem Lett. 2006. PMID: 16723225

4

Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring.

Metobo SE, Jin H, Tsiang M, Kim CU. Metobo SE, et al. Among authors: jin h. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3985-8. doi: 10.1016/j.bmcl.2006.05.018. Epub 2006 May 24. Bioorg Med Chem Lett. 2006. PMID: 16723226

5

Tricyclic HIV integrase inhibitors: potent and orally bioavailable C5-aza analogs.

Jin H, Wright M, Pastor R, Mish M, Metobo S, Jabri S, Lansdown R, Cai R, Pyun P, Tsiang M, Chen X, Kim CU. Jin H, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1388-91. doi: 10.1016/j.bmcl.2008.01.018. Epub 2008 Jan 9. Bioorg Med Chem Lett. 2008. PMID: 18207398

6

Tricyclic HIV integrase inhibitors V. SAR studies on the benzyl moiety.

Jin H, Metobo S, Jabri S, Mish M, Lansdown R, Chen X, Tsiang M, Wright M, Kim CU. Jin H, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2263-5. doi: 10.1016/j.bmcl.2009.02.092. Epub 2009 Feb 27. Bioorg Med Chem Lett. 2009. PMID: 19285389

7

Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors.

Chen X, Tsiang M, Yu F, Hung M, Jones GS, Zeynalzadegan A, Qi X, Jin H, Kim CU, Swaminathan S, Chen JM. Chen X, et al. Among authors: jin h. J Mol Biol. 2008 Jul 11;380(3):504-19. doi: 10.1016/j.jmb.2008.04.054. Epub 2008 May 1. J Mol Biol. 2008. PMID: 18565342

8

Design, synthesis and evaluation of a series of novel fumagillin analogues.

Fardis M, Pyun HJ, Tario J, Jin H, Kim CU, Ruckman J, Lin Y, Green L, Hicke B. Fardis M, et al. Among authors: jin h. Bioorg Med Chem. 2003 Nov 17;11(23):5051-8. doi: 10.1016/j.bmc.2003.08.031. Bioorg Med Chem. 2003. PMID: 14604668

9

Investigation of novel fumagillin analogues as angiogenesis inhibitors.

Pyun HJ, Fardis M, Tario J, Yang CY, Ruckman J, Henninger D, Jin H, Kim CU. Pyun HJ, et al. Among authors: jin h. Bioorg Med Chem Lett. 2004 Jan 5;14(1):91-4. doi: 10.1016/j.bmcl.2003.10.008. Bioorg Med Chem Lett. 2004. PMID: 14684305

10

Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase.

Jones GS, Yu F, Zeynalzadegan A, Hesselgesser J, Chen X, Chen J, Jin H, Kim CU, Wright M, Geleziunas R, Tsiang M. Jones GS, et al. Among authors: jin h. Antimicrob Agents Chemother. 2009 Mar;53(3):1194-203. doi: 10.1128/AAC.00984-08. Epub 2008 Dec 22. Antimicrob Agents Chemother. 2009. PMID: 19104010 Free PMC article.

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