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An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.
Mintz PJ, Cardó-Vila M, Ozawa MG, Hajitou A, Rangel R, Guzman-Rojas L, Christianson DR, Arap MA, Giordano RJ, Souza GR, Easley J, Salameh A, Oliviero S, Brentani RR, Koivunen E, Arap W, Pasqualini R. Mintz PJ, et al. Among authors: salameh a. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2182-7. doi: 10.1073/pnas.0807543105. Epub 2009 Jan 23. Proc Natl Acad Sci U S A. 2009. PMID: 19168626 Free PMC article.
From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway.
Giordano RJ, Cardó-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawke DH, Valente AP, Almeida FC, Nör JE, Sidman RL, Pasqualini R, Arap W. Giordano RJ, et al. Among authors: salameh a. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5112-7. doi: 10.1073/pnas.0915141107. Epub 2010 Feb 26. Proc Natl Acad Sci U S A. 2010. PMID: 20190181 Free PMC article.
Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment.
Guzman-Rojas L, Rangel R, Salameh A, Edwards JK, Dondossola E, Kim YG, Saghatelian A, Giordano RJ, Kolonin MG, Staquicini FI, Koivunen E, Sidman RL, Arap W, Pasqualini R. Guzman-Rojas L, et al. Among authors: salameh a. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1637-42. doi: 10.1073/pnas.1120790109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22307623 Free PMC article.
PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3.
Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, Lima LA, Carraro DM, Oliviero S, Kolonin MG, Sidman RL, Do KA, Troncoso P, Logothetis CJ, Brentani RR, Calin GA, Cavenee WK, Dias-Neto E, Pasqualini R, Arap W. Salameh A, et al. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8403-8. doi: 10.1073/pnas.1507882112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080435 Free PMC article.
Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis.
Christianson DR, Dobroff AS, Proneth B, Zurita AJ, Salameh A, Dondossola E, Makino J, Bologa CG, Smith TL, Yao VJ, Calderone TL, O'Connell DJ, Oprea TI, Kataoka K, Cahill DJ, Gershenwald JE, Sidman RL, Arap W, Pasqualini R. Christianson DR, et al. Among authors: salameh a. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2521-6. doi: 10.1073/pnas.1424994112. Epub 2015 Feb 6. Proc Natl Acad Sci U S A. 2015. PMID: 25659743 Free PMC article.
Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer.
Staquicini FI, Qian MD, Salameh A, Dobroff AS, Edwards JK, Cimino DF, Moeller BJ, Kelly P, Nunez MI, Tang X, Liu DD, Lee JJ, Hong WK, Ferrara F, Bradbury AR, Lobb RR, Edelman MJ, Sidman RL, Wistuba II, Arap W, Pasqualini R. Staquicini FI, et al. Among authors: salameh a. J Biol Chem. 2015 Mar 20;290(12):7345-59. doi: 10.1074/jbc.M114.630525. Epub 2015 Jan 26. J Biol Chem. 2015. PMID: 25623065 Free PMC article.
Endothelial cell adhesion to the extracellular matrix induces c-Src-dependent VEGFR-3 phosphorylation without the activation of the receptor intrinsic kinase activity.
Galvagni F, Pennacchini S, Salameh A, Rocchigiani M, Neri F, Orlandini M, Petraglia F, Gotta S, Sardone GL, Matteucci G, Terstappen GC, Oliviero S. Galvagni F, et al. Among authors: salameh a. Circ Res. 2010 Jun 25;106(12):1839-48. doi: 10.1161/CIRCRESAHA.109.206326. Epub 2010 Apr 29. Circ Res. 2010. PMID: 20431062
240 results