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Wnt5A activates the calpain-mediated cleavage of filamin A.
O'Connell MP, Fiori JL, Baugher KM, Indig FE, French AD, Camilli TC, Frank BP, Earley R, Hoek KS, Hasskamp JH, Elias EG, Taub DD, Bernier M, Weeraratna AT. O'Connell MP, et al. Among authors: frank bp. J Invest Dermatol. 2009 Jul;129(7):1782-9. doi: 10.1038/jid.2008.433. Epub 2009 Jan 29. J Invest Dermatol. 2009. PMID: 19177143 Free PMC article.
Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility.
Camilli TC, Xu M, O'Connell MP, Chien B, Frank BP, Subaran S, Indig FE, Morin PJ, Hewitt SM, Weeraratna AT. Camilli TC, et al. Among authors: frank bp. Pigment Cell Melanoma Res. 2011 Feb;24(1):175-86. doi: 10.1111/j.1755-148X.2010.00792.x. Epub 2010 Dec 1. Pigment Cell Melanoma Res. 2011. PMID: 20955350 Free PMC article.
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease.
Martin B, Golden E, Carlson OD, Pistell P, Zhou J, Kim W, Frank BP, Thomas S, Chadwick WA, Greig NH, Bates GP, Sathasivam K, Bernier M, Maudsley S, Mattson MP, Egan JM. Martin B, et al. Among authors: frank bp. Diabetes. 2009 Feb;58(2):318-28. doi: 10.2337/db08-0799. Epub 2008 Nov 4. Diabetes. 2009. PMID: 18984744 Free PMC article.
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